Question · asked by 1 review

220 mg zinc sulphate supplement containing 50 mg elemental zinc vs placebo: Ulcer healing

It is very uncertain whether 220 mg zinc sulphate supplement containing 50 mg elemental zinc changes ulcer healing (absolute change in individual parameters of ulcer… compared with placebo (very low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
220 mg zinc sulphate supplement containing 50 mg elemental zinc vs placebo
Ulcer healing (absolute change in individual parameters of ulcer dimensions over time: mean (SD) cm wound length reduction) · people with diabetes and foot ulcers
It is very uncertain whether 220 mg zinc sulphate supplement containing 50 mg elemental zinc changes ulcer healing (absolute change in individual parameters of ulcer… compared with placebo (very low certainty).
Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane Headline outcomes only
no estimate extracted1 study · 60 participantsVery low
220 mg zinc sulphate supplement containing 50 mg elemental zinc vs placebo
Ulcer healing (absolute change in individual parameters of ulcer dimensions over time: mean (SD) cm wound depth reduction) · people with diabetes and foot ulcers
It is very uncertain whether 220 mg zinc sulphate supplement containing 50 mg elemental zinc changes ulcer healing (absolute change in individual parameters of ulcer… compared with placebo (very low certainty).
Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane Headline outcomes only
no estimate extracted1 study · 60 participantsVery low
220 mg zinc sulphate supplement containing 50 mg elemental zinc vs placebo
Ulcer healing (absolute change in individual parameters of ulcer dimensions over time: mean (SD) cm wound width reduction) · people with diabetes and foot ulcers
It is very uncertain whether 220 mg zinc sulphate supplement containing 50 mg elemental zinc changes ulcer healing (absolute change in individual parameters of ulcer… compared with placebo (very low certainty).
Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane Headline outcomes only
no estimate extracted1 study · 60 participantsVery low
220 mg zinc sulphate supplement containing 50 mg elemental zinc vs placebo
Ulcer healing (proportion of ulcers healed) · people with diabetes and foot ulcers
The review found no eligible studies for this question.
Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane Headline outcomes only
no estimate extractedNot reportedNo studies found

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Nutritional interventions for treating foot ulcers in people with diabetes
2020 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.