Findings

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Evidence found and GRADE certainty

4,534 questions · 5,247 findings · 456 reviews

No studies found 1,142 · 21.8%GRADE not reported 1,503 · 28.6%Very low 1,040 · 19.8%Low 869 · 16.6%Moderate 554 · 10.6%High 139 · 2.6%

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2 mm titanium plates vs 2.5 mm bioresorbable plates

Restoration of function (inability to chew hard food) · Adults (16 to 68 years) with mandibular fractures excluding condylar involvement

2 mm titanium plates showed no clear difference in restoration of function (inability to chew hard food) compared with 2.5 mm bioresorbable plates; GRADE not reported.

1 finding from 1 review

Locking plate vs 2 mm non-locking titanium plates

Post-operative adverse events and complications (paraesthesia, swelling, segmental mobility) · Adults (16 to 68 years) with mandibular fractures excluding condylar involvement
1 finding from 1 review
  • Agarwal 2011: paraesthesia in one participant in the non-locking plate group (resolved by 3 months), none in the locking group; infection rates similar at 6 weeks and 3 months; post-operative swelling in 20% of both…
    1 study
    GRADE not reported

2 mm titanium plates vs 2.5 mm bioresorbable plates

Post-operative neurosensory disturbance (mental nerve paraesthesia) · Adults (16 to 68 years) with mandibular fractures excluding condylar involvement

2 mm titanium plates led to higher post-operative neurosensory disturbance (mental nerve paraesthesia) compared with 2.5 mm bioresorbable plates; GRADE not reported.

1 finding from 1 review

2 mm titanium plates vs 2.5 mm bioresorbable plates

Requirement for additional (surgical) interventions (plate removal / re-operation) · Adults (16 to 68 years) with mandibular fractures excluding condylar involvement
1 finding from 1 review
  • Plate removal was statistically more likely in the titanium group (Fisher's exact P<0.05); infection led to plate removal in one titanium participant at 2 months and a further 4/21 (19%) titanium participants (six…
    1 study
    GRADE not reported

Locking plate vs 2 mm non-locking titanium plates

Requirement for additional (surgical) interventions · Adults (16 to 68 years) with mandibular fractures excluding condylar involvement
1 finding from 1 review
  • Only Collins 2004 provided data: 6/122 participants had minor complications (three in each group); five required surgical removal of the locking plates and one post-operative malocclusion was managed with elastic…
    1 study · 122 participants
    GRADE not reported

Two lag screws vs One lag screw (with arch bars and IMF)

Post-operative adverse events and complications · Adults (16 to 68 years) with mandibular fractures excluding condylar involvement
1 finding from 1 review
  • Three participants in the two-lag-screws group experienced complications: malocclusion (one) and mental-nerve paraesthesia (two, resolved after 3 months). There were no post-operative complications in the one-lag-screw…
    1 study
    GRADE not reported

3-dimensional (3D) miniplates vs Standard (Champy) plates

Post-operative adverse events and complications · Adults (16 to 68 years) with mandibular fractures excluding condylar involvement
1 finding from 1 review
  • Jain 2010 (3D group): segmental mobility (two), proximity to mental nerve or roots (two), radiologically unsatisfactory reduction (one) and unsatisfactory fixation (four) vs one (standard); only fixation differed…
    2 studies
    GRADE not reported

Locking plate vs 2 mm non-locking titanium plates

Drop-out rate due to protocol deviation · Adults (16 to 68 years) with mandibular fractures excluding condylar involvement
1 finding from 1 review
  • Early premature removal of IMF (from hours up to 2 weeks) was reported in 13 of the 90 participants analysed (Collins 2004); participants released their own IMF or reported that "the wires fell off".
    1 study · 90 participants
    GRADE not reported

2 mm titanium plates vs 2.5 mm bioresorbable plates

Post-operative pain (residual pain, any severity) · Adults (16 to 68 years) with mandibular fractures excluding condylar involvement

2 mm titanium plates showed no clear difference in post-operative pain (residual pain, any severity) compared with 2.5 mm bioresorbable plates; GRADE not reported.

1 finding from 1 review

Locking plate vs 2 mm non-locking titanium plates

Restoration of function (functional occlusion; bite force as surrogate) · Adults (16 to 68 years) with mandibular fractures excluding condylar involvement
1 finding from 1 review
  • Functional occlusion was achieved in all participants in both intervention groups (Agarwal 2011); the measurement of this outcome was not clearly reported. Bite force was reported as a surrogate/proxy outcome.
    1 study
    GRADE not reported