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What do systematic reviews say?

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Evidence found and GRADE certainty

4,749 questions · 14,273 findings · 834 reviews

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No studies found 3,655 · 25.6%GRADE not reported 2,115 · 14.8%Very low 3,646 · 25.5%Low 3,034 · 21.3%Moderate 1,503 · 10.5%High 320 · 2.2%

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IVIg vs placebo

Response at 3 months · adults with renal vasculitis

Intravenous immunoglobulin may leads to higher response at 3 months compared with placebo (low certainty).

1 finding from 1 review

IVIg vs placebo

Relapse at 3 months · adults with renal vasculitis

Intravenous immunoglobulin showed no clear difference in relapse at 3 months compared with placebo (low certainty).

1 finding from 1 review

IVIg vs placebo

Adverse events · adults with renal vasculitis

Intravenous immunoglobulin may leads to higher adverse events compared with placebo (low certainty).

1 finding from 1 review

Intervention not reported

Sustained remission · adults with renal vasculitis

The intervention may leads to higher sustained remission (low certainty).

1 finding from 1 review

Intervention not reported

Relapse · adults with renal vasculitis

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Total number of adverse events · adults with renal vasculitis

The intervention showed no clear difference in total number of adverse events (low certainty).

1 finding from 1 review

Intervention not reported

Serious infections · adults with renal vasculitis

The intervention may leads to higher serious infections (low certainty).

1 finding from 1 review

Mohs micrographic surgery vs surgical excision

Recurrence · adults with basal cell carcinoma of the skin

Mohs micrographic surgery showed no clear difference in recurrence at 3 years compared with surgical excision (low certainty).

2 findings from 1 review

Radiotherapy vs surgical excision

Recurrence · adults with basal cell carcinoma of the skin

Radiotherapy may leads to higher recurrence at 3 years compared with surgical excision (with or without frozen section margin control) (low certainty).

2 findings from 1 review

Radiotherapy vs surgical excision

Cosmetic outcome (good/excellent) · adults with basal cell carcinoma of the skin

Radiotherapy probably leads to lower cosmetic outcome (good/excellent) compared with surgical excision (with or without frozen section margin control) (moderate certainty).

1 finding from 1 review