Findings

What do systematic reviews say?

754 questions · 769 findings · 35 reviews · Kidney and Transplant

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No studies found 228 · 29.6%GRADE not reported 3 · 0.4%Very low 215 · 28%Low 245 · 31.9%Moderate 74 · 9.6%High 4 · 0.5%

Topical treatments vs placebo

Capsaicin cream VAS and Duo’s score · uraemic pruritus

1 finding from 1 review

Interventions for itch in people with advanced chronic kidney disease 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 112 participants
Moderate

Topical treatments vs placebo

Pramoxine lotion VAS(0 to 10 cm) · uraemic pruritus

1 finding from 1 review

Interventions for itch in people with advanced chronic kidney disease 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 27 participants
Very low

Topical treatments vs placebo

Calcineurin inhibitor VAS(0 to 10 cm) · uraemic pruritus

1 finding from 1 review

Interventions for itch in people with advanced chronic kidney disease 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 80 participants
Very low

Topical treatments vs placebo

Dead Sea lotion 1 to 5 severity score · uraemic pruritus

1 finding from 1 review

Interventions for itch in people with advanced chronic kidney disease 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 41 participants
Very low

Topical treatments vs placebo

Cromolyn cream VAS (0 to 5 cm) · uraemic pruritus

1 finding from 1 review

Interventions for itch in people with advanced chronic kidney disease 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
Low

Topical treatments vs placebo

Baby oil Itch Severity Scale(0 to 21) · uraemic pruritus

1 finding from 1 review

Interventions for itch in people with advanced chronic kidney disease 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 125 participants
Low

Topical treatments vs placebo

L‐arginine salve 0 to 3 severity score · uraemic pruritus

1 finding from 1 review

Interventions for itch in people with advanced chronic kidney disease 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 48 participants
Low

Topical treatments vs placebo

Polyunsaturated fatty acids VAS (0 to 10 cm) Duo score · uraemic pruritus

1 finding from 1 review

Interventions for itch in people with advanced chronic kidney disease 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 78 participants
Low

Intervention not reported

Polyunsaturated fatty acids 0 to 5severity score · uraemic pruritus

1 finding from 1 review

Interventions for itch in people with advanced chronic kidney disease 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 22 participants
Low

Intervention not reported

L‐carnitine VAS (0 to 6 cm) · uraemic pruritus

1 finding from 1 review

Interventions for itch in people with advanced chronic kidney disease 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 12 participants
Low

Intervention not reported

Zinc sulfate VAS (0 to 10 cm) · uraemic pruritus

1 finding from 1 review

Interventions for itch in people with advanced chronic kidney disease 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 76 participants
Moderate

Intervention not reported

Ergocalciferol 21 point scale · uraemic pruritus

1 finding from 1 review

Interventions for itch in people with advanced chronic kidney disease 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 50 participants
Low

Intervention not reported

Turmeric Duo score (5 to 40) · uraemic pruritus

1 finding from 1 review

Interventions for itch in people with advanced chronic kidney disease 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 100 participants
Moderate

Intervention not reported

Fumaria parviflora VAS (0 to 10 cm) · uraemic pruritus

1 finding from 1 review

Interventions for itch in people with advanced chronic kidney disease 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 63 participants
Low

Intervention not reported

High flux/permeability dialysis VAS (0 to 10 cm) · uraemic pruritus

1 finding from 1 review

Interventions for itch in people with advanced chronic kidney disease 2020 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 202 participants
Low

Intervention not reported

HD with haemoperfusion VAS (0 to 10 cm) · uraemic pruritus

1 finding from 1 review

Interventions for itch in people with advanced chronic kidney disease 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 90 participants
Low

Intervention not reported

UV‐B Duo score, VAS, and %improvement · uraemic pruritus

1 finding from 1 review

Interventions for itch in people with advanced chronic kidney disease 2020 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 86 participants
Low

Intervention not reported

Thermal therapy VAS (0 to 10 cm) · uraemic pruritus

1 finding from 1 review

Interventions for itch in people with advanced chronic kidney disease 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 41 participants
Low

ACUTE: Serelaxin vs placebo

Death (any cause) · heart failure with chronic kidney disease

ACUTE: Serelaxin showed no clear difference in death (any cause) compared with placebo (low certainty).

1 finding from 1 review

Pharmacological interventions for heart failure in people with chronic kidney disease 2020 · Cochrane Headline outcomes only
RR 0.59 [0.34, 1.02]
2 studies · 1395 participants
Low

CHRONIC: ACEi or ARB vs placebo

Death (any cause) ( · heart failure with chronic kidney disease

CHRONIC: ACEi or ARB showed no clear difference in death (any cause) ( compared with placebo (low certainty).

1 finding from 1 review

Pharmacological interventions for heart failure in people with chronic kidney disease 2020 · Cochrane Headline outcomes only
RR 0.85 [0.7, 1.02]
4 studies · 5003 participants
Low