Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

484 questions · 512 findings · 35 reviews · Common Mental Disorders

No studies found 137 · 26.8%GRADE not reported 12 · 2.3%Very low 156 · 30.5%Low 136 · 26.6%Moderate 60 · 11.7%High 11 · 2.1%

Comparison 7: compliance enhancement plus treatment as usual (i.e., standard disposition planning) vs treatment

Repetition of SH at 6 months' · children and adolescents who engage in SH.

It is very uncertain whether comparison 7: compliance enhancement plus treatment as usual (i.e.,… changes repetition of SH by six months compared with treatment (very low certainty).

1 finding from 1 review

Propranolol vs placebo

Treatment efficacy CAPS, CIDI · adult participants (18 years and older) who have been exposed to any traumatic events, but who did not meet the diagnostic criteria for…

Propranolol showed no clear difference in treatment efficacy CAPS, CIDI compared with placebo (low certainty).

1 finding from 1 review

Hydrocortisone vs placebo

Treatment efficacy CAPS, SCID‐IV, PTSS‐10Q‐I · adult participants (18 years and older) who have been exposed to any traumatic events, but who did not meet the diagnostic criteria for…

Hydrocortisone probably leads to lower treatment efficacy CAPS, SCID‐IV, PTSS‐10Q‐I compared with placebo (moderate certainty).

1 finding from 1 review

New‐generation antidepressants vs placebo

Treatment response (post‐treatment score on self report and clinician‐rated scales) · somatoform disorders in adults

It is very uncertain whether new‐generation antidepressants changes treatment response (post‐treatment score on self report and… compared with placebo (very low certainty).

1 finding from 1 review