Findings

What do systematic reviews say?

423 questions · 477 findings · 107 reviews

No studies found 44 · 9.2%GRADE not reported 97 · 20.3%Very low 165 · 34.6%Low 113 · 23.7%Moderate 41 · 8.6%High 17 · 3.6%

FEV1 · patients with acute asthma

ICS showed no clear difference in FEV1 at 3 to 4 hours compared with placebo (moderate certainty).

1 finding from 1 review

Nausea and vomiting · patients with acute asthma

ICS showed no clear difference in adverse effects ‐ nausea/vomiting compared with placebo (low certainty).

1 finding from 1 review

Early use of inhaled corticosteroids in the emergency department treatment of acute asthma 2012 · Cochrane Headline outcomes only
OR 0.32 [0.03, 3.18]
1 study · 94 participants
Low

Hospital admissions · patients with acute asthma

ICS showed no clear difference in hospital admission compared with systemic corticosteroids (low certainty).

1 finding from 1 review

Early use of inhaled corticosteroids in the emergency department treatment of acute asthma 2012 · Cochrane Headline outcomes only
OR 0.56 [0.25, 1.24]
10 studies · 763 participants
Low