Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,741 questions · 1,821 findings · 207 reviews

No studies found 297 · 16.3%GRADE not reported 191 · 10.5%Very low 333 · 18.3%Low 466 · 25.6%Moderate 414 · 22.7%High 120 · 6.6%

Intervention not reported

Alcohol‐related problems: 4+ months—individual face‐to‐face normative feedback · university or college students

The intervention showed no clear difference in alcohol‐related problems: 4+ months—individual face‐to‐face… (moderate certainty).

1 finding from 1 review

Intervention not reported

Frequency: 4+ months—individual face‐to‐face normative feedback · university or college students

The intervention showed no clear difference in frequency: 4+ months—individual face‐to‐face normative feedback (moderate certainty).

1 finding from 1 review

Intervention not reported

Typical BAC: 4+ months—individual face‐to‐face normative feedback · university or college students

The intervention showed no clear difference in typical BAC: 4+ months—individual face‐to‐face normative feedback (moderate certainty).

1 finding from 1 review

Surgical anchorage (mini-screw or mid-palatal implant) vs Conventional anchorage (headgear, transpalatal/palatal arch, etc.)

Residual overjet at the end of treatment · Patients of any age undergoing orthodontic treatment with fixed appliances and requiring anchorage (adolescents to adults up to 48-54 years)

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Response rate at post‐treatment (as defined in individual studies) · women with postnatal depression

It is very uncertain whether the intervention changes response rate at post‐treatment (as defined in individual studies) (very low certainty).

1 finding from 1 review

Intervention not reported

Remission rate at post‐treatment (as defined in individual studies) · women with postnatal depression

It is very uncertain whether the intervention changes remission rate at post‐treatment (as defined in individual studies) (very low certainty).

1 finding from 1 review

Intervention not reported

Individual counselling · Employees who smoke

The intervention probably leads to higher individual counselling (moderate certainty).

1 finding from 1 review

Imiquimod 5% cream with tazarotene 0.1% gel vs Imiquimod 5% cream alone

Primary outcome: Histological complete response ( available‐case analysis) No residual LM in staged excision 2 months post‐treatment · participants with melanoma in situ, including lentigo maligna

Imiquimod 5% cream with tazarotene 0.1% gel showed no clear difference in primary outcome: Histological complete response (intention‐to‐treat)… compared with imiquimod 5% cream alone (low certainty).

2 findings from 1 review