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Evidence found and GRADE certainty

4,411 questions · 5,986 findings · 226 reviews · Oral Health

No studies found 1,305 · 21.8%GRADE not reported 2,988 · 49.9%Very low 1,030 · 17.2%Low 476 · 8%Moderate 156 · 2.6%High 31 · 0.5%

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Thalidomide (immunomodulator) vs Placebo or no treatment

Outcome not reported · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…

The review found no eligible studies for this question.

1 finding from 1 review

Dietary counselling tailored to a Stage of Change (Transtheoretical Model) to increase fruit and vegetable intake (two counselling sessions) vs usual care

Fruit consumption behaviour: proportion in the Action Stage of Change (versus Pre-Action) · Edentulous patients aged 45 to 80 years attending dental-student teaching clinics for replacement dentures, Newcastle Dental Hospital, UK
1 finding from 1 review

Erbium:YAG laser vs Flap elevation at implant exposure

Biological complications · Patients undergoing implant exposure (second-stage surgery)

Erbium:YAG laser (implant exposure) showed no clear difference in biological complications compared with flap elevation at implant exposure; GRADE not reported.

1 finding from 1 review

Intraoral vertical ramus osteotomy (IVRO) vs Sagittal split ramus osteotomy (SSRO)

Stability of correction: sagittal changes of B-point (1 week to 1 year) · Adults (16 years of age or older) with an Angle Class III malocclusion (prominent lower front teeth); people with syndromes, clefts or…

Intraoral vertical ramus osteotomy (IVRO) showed no clear difference in stability of correction: sagittal changes of B-point (1 week to 1… compared with sagittal split ramus osteotomy (SSRO); GRADE not reported.

1 finding from 1 review

Sodium hypochlorite 5.25% vs Sodium hypochlorite 5.25% with hydrogen peroxide 3%

Proportion of participants or samples with positive bacterial growth culture, up to 72 hours after the procedure · Patients aged 14 to 78 years with mature permanent teeth (fully formed roots), single or multi-rooted, with pulpal or periapical…

The review found no eligible studies for this question.

1 finding from 1 review

Metal-free implant abutments (zirconia) vs Metal implant abutments (titanium)

Abutment/crown fracture and marginal bone level (3 years) · Patients with single-tooth implant crowns; split-mouth, 3-year
1 finding from 1 review

Topical ciclosporin 1.5% gel vs Topical clobetasol propionate 0.025% gel

Participant‐reported pain relief of 50% or greater · People with erosive oral lichen planus

Topical ciclosporin 1.5% gel showed no clear difference in pain (>=50% improvement in symptoms) compared with topical clobetasol propionate 0.025% gel; GRADE not reported.

1 finding from 1 review

Sodium hypochlorite 5.25% with hydrogen peroxide 3% vs Normal saline

Change in periapical radiolucency (radiography or CBCT), up to 1 year after treatment · Patients aged 14 to 78 years with mature permanent teeth (fully formed roots), single or multi-rooted, with pulpal or periapical…

The review found no eligible studies for this question.

1 finding from 1 review

Sodium hypochlorite 1.3% with MTAD final rinse vs Sodium hypochlorite 1.3% with normal saline final rinse

Proportion of participants with moderate to severe pain 72 hours to 14 days after the procedure · Patients aged 14 to 78 years with mature permanent teeth (fully formed roots), single or multi-rooted, with pulpal or periapical…

The review found no eligible studies for this question.

1 finding from 1 review

Individually designed, patient-centred preventive programme: dietary counselling (snacking timing, regular meals, fermentable carbohydrates) plus toothbrushing counselling, delivered by trained dental hygienists (a multi-intervention) vs Basic prevention offered as standard in public dental clinics

Drinking sports drinks no more than once per week · Children aged 11 to 12 years with at least one active initial caries lesion, screened in a town in Finland
1 finding from 1 review

Fixed dental prosthesis (cantilever FDP) vs Removable dental prosthesis (RDP)

Patient satisfaction with prosthesis · Patients with a shortened dental arch (missing posterior teeth)

Fixed dental prosthesis (cantilever FDP) showed no clear difference in patient satisfaction with prosthesis compared with removable dental prosthesis (RDP); GRADE not reported.

1 finding from 1 review

Clofazimine (100 mg daily for 30 days, then 100 mg every other day) vs placebo

Adverse effects · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…
1 finding from 1 review

LongoVital (herbal component alone) vs placebo

Number of days of ulcers (monthly average) · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…

LongoVital (herbal component alone) showed no clear difference in number of days of ulcers (monthly average) compared with placebo; GRADE not reported.

1 finding from 1 review

Erbium:YAG laser vs Air-abrasive device (Perio-Flow)

Marginal bone level change · People with at least one dental implant affected by perimplantitis

Er:YAG laser showed no clear difference in radiographic marginal bone level change compared with air-abrasive device (Perio-Flow); GRADE not reported.

1 finding from 1 review

Iontophoretically applied corticosteroids

Outcome not reported · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria

The review found no eligible studies for this question.

1 finding from 1 review

Crestal incision vs Vestibular incision

Biological complications · People with dental implants

Crestal incision led to lower biological complications compared with vestibular incision; GRADE not reported.

1 finding from 1 review