Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,756 questions · 11,779 findings · 747 reviews · Headline outcomes only

No studies found 3,205 · 27.2%GRADE not reported 628 · 5.3%Very low 3,261 · 27.7%Low 2,913 · 24.7%Moderate 1,453 · 12.3%High 319 · 2.7%

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Intervention not reported

Gait assessment · participants with resistant CTEV

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Health‐related quality of life · participants with resistant CTEV

The review found no eligible studies for this question.

1 finding from 1 review

IFN‐α + PUVA vs PUVA

Improvement of quality of life · people with mycosis fungoides

The review found no eligible studies for this question.

1 finding from 1 review

Bexarotene + PUVA vs PUVA

Common adverse effects ‐ Photosensitivity (Time point of measurement: up to 16 weeks) · people with mycosis fungoides

Bexarotene + PUVA showed no clear difference in common adverse effects ‐ Photosensitivity (Time point of… compared with PUVA alone (low certainty).

1 finding from 1 review

Bexarotene + PUVA vs PUVA

Complete response · people with mycosis fungoides

Bexarotene + PUVA showed no clear difference in complete response (Time point of measurement: up to 16 weeks) compared with PUVA alone (low certainty).

1 finding from 1 review

Bexarotene + PUVA vs PUVA

Objective response rate · people with mycosis fungoides

Bexarotene + PUVA showed no clear difference in objective response rate (Time point of measurement: up to 16 weeks) compared with PUVA alone (low certainty).

1 finding from 1 review

IFN‐α + acitretin vs IFN‐α + PUVA

Adverse event (flu‐like symptoms) · people with mycosis fungoides

IFN‐α + acitretin showed no clear difference in common adverse effects ‐ Flu‐like symptoms (Time point of… compared with IFN‐α + PUVA (low certainty).

1 finding from 1 review

IFN‐α + acitretin vs IFN‐α + PUVA

Complete response · people with mycosis fungoides

IFN‐α + acitretin may leads to lower complete response (Time point of measurement: up to 48 weeks or… compared with IFN‐α + PUVA (low certainty).

1 finding from 1 review

IFN‐α + PUVA vs PUVA

Complete response · people with mycosis fungoides

IFN‐α + PUVA showed no clear difference in complete response (CR) compared with PUVA alone (low certainty).

1 finding from 1 review

Extracorporeal photopheresis vs PUVA

Complete response · people with mycosis fungoides

It is very uncertain whether extracorporeal photopheresis changes complete response (Time point of measurement: three months of PUVA… compared with PUVA (very low certainty).

1 finding from 1 review