Blood transfusion · women undergoing breast surgery
It is very uncertain whether NSAID changes need for blood transfusion compared with placebo (very low certainty).
1 finding from 1 review
Other side effects of NSAID use · women undergoing breast surgery
NSAID showed no clear difference in other side effects of NSAID use compared with placebo (low certainty).
1 finding from 1 review
Opioid use within 24 (± 12) hours of surgery · women undergoing breast surgery
1 finding from 1 review
Specific behaviour ‐ agitation
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Psychosis ‐ presented in units of NPI‐NH P (higher is worse)d ‐ 3364 persons in 12 RCTs of 3 to 12 weeks
1 finding from 1 review
no estimate extracted
Studies not reported
Moderate
Response for psychosis ‐ as defined by authors of RCTs ‐ 1958 persons in 7 RCTs of 3 to 12 weeks
1 finding from 1 review
no estimate extracted
Studies not reported
Low
Adverse effects/events ‐ extrapyramidal symptoms ‐ medium term Number of instances of extrapyramidal symptoms
1 finding from 1 review
no estimate extracted
Studies not reported
Moderate
Somnolence
1 finding from 1 review
no estimate extracted
Studies not reported
High
Death ‐ 5032 persons in 17 RCTs of 3 to 12 weeks ___________________________________________
1 finding from 1 review
no estimate extracted
Studies not reported
Moderate
Response for agitation ‐ as defined by authors of RCTs ‐ 1303 persons in 4 RCTs of 3 to 12 weeks
1 finding from 1 review
no estimate extracted
Studies not reported
Moderate
Psychosis ‐ presented in units of NPI‐NH P (higher is worse)d ‐ 3364 persons in 12 RCTs of 3 to 12 weeks
1 finding from 1 review
no estimate extracted
Studies not reported
Low
Response for psychosis ‐ as defined by authors of RCTs ‐ 1958 persons in 7 RCTs of 3 to 12 weeks
1 finding from 1 review
no estimate extracted
Studies not reported
Low
Adverse effects/events ‐ extrapyramidal symptoms ‐ medium term Number of instances of extrapyramidal symptoms
1 finding from 1 review
no estimate extracted
Studies not reported
High
Somnolence
1 finding from 1 review
no estimate extracted
Studies not reported
Moderate
Death ‐ 5032 persons in 17 RCTs of 3 to 12 weeks ___________________________________________
1 finding from 1 review
no estimate extracted
Studies not reported
Low
Specific behaviour ‐ agitation
1 finding from 1 review
no estimate extracted
Studies not reported
Moderate
Response for agitation ‐ as defined by authors of RCTs ‐ 1303 persons in 4 RCTs of 3 to 12 weeks
1 finding from 1 review
no estimate extracted
Studies not reported
Moderate
Cognitive function · vascular dementia and other vascular cognitive impairments
1 finding from 1 review
Serious adverse events (excluding death) at 24 weeks · vascular dementia and other vascular cognitive impairments
Donepezil 10 mg showed no clear difference in serious adverse events (excluding death) at 24 weeks compared with placebo (moderate certainty).
1 finding from 1 review
Cognitive function · vascular dementia and other vascular cognitive impairments
1 finding from 1 review