Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,320 questions · 4,561 findings · 388 reviews

No studies found 1,138 · 25%GRADE not reported 886 · 19.4%Very low 1,014 · 22.2%Low 849 · 18.6%Moderate 543 · 11.9%High 131 · 2.9%

Locking plate vs 2 mm non-locking titanium plates

Drop-out rate due to protocol deviation · Adults (16 to 68 years) with mandibular fractures excluding condylar involvement
1 finding from 1 review
  • Early premature removal of IMF (from hours up to 2 weeks) was reported in 13 of the 90 participants analysed (Collins 2004); participants released their own IMF or reported that "the wires fell off".
    1 study · 90 participants
    GRADE not reported

2 mm titanium plates vs 2.5 mm bioresorbable plates

Post-operative pain (residual pain, any severity) · Adults (16 to 68 years) with mandibular fractures excluding condylar involvement

2 mm titanium plates showed no clear difference in post-operative pain (residual pain, any severity) compared with 2.5 mm bioresorbable plates; GRADE not reported.

1 finding from 1 review

Locking plate vs 2 mm non-locking titanium plates

Restoration of function (functional occlusion; bite force as surrogate) · Adults (16 to 68 years) with mandibular fractures excluding condylar involvement
1 finding from 1 review
  • Functional occlusion was achieved in all participants in both intervention groups (Agarwal 2011); the measurement of this outcome was not clearly reported. Bite force was reported as a surrogate/proxy outcome.
    1 study
    GRADE not reported

LHWs to promote immunisation uptake in children vs usual care

Immunisation schedule up to date Interviews with mothers, record reviews · patients with improving immunisation uptake among children < 2 years whose vaccination is not up to date

LHWs to promote immunisation uptake in children probably leads to higher immunisation schedule up to date Interviews with mothers, record… compared with usual care (moderate certainty).

1 finding from 1 review

LHWs vs usual care

Morbidity e.g. fever, diarrhoea, ARI Verbal reports obtained during home visits, record reviews · patients with reducing mortality and morbidity in children <5 years

LHWs may leads to lower morbidity e.g. fever, diarrhoea, ARI Verbal reports obtained during… compared with usual care (low certainty).

1 finding from 1 review

LHWs vs usual care

Morbidity ‐ care seeking practice hospital record review · patients with reducing mortality and morbidity in children <5 years

LHWs showed no clear difference in morbidity ‐ care seeking practice hospital record review compared with usual care (low certainty).

1 finding from 1 review

Binocular iPad treatment vs occlusion therapy

Visual acuity · 5‐ to 8‐year‐old children with amblyopia
2 findings from 1 review

Binocular iPad treatment vs occlusion therapy

Change in the interocular difference in contrast sensitivity Any validated test, from baseline to 16 (± 2) weeks · 5‐ to 8‐year‐old children with amblyopia

The review found no eligible studies for this question.

1 finding from 1 review

Binocular iPad treatment vs occlusion therapy

Measurable change in stereopsis after 8 (± 2) weeks and 16 (± 2) weeks of intervention 'Real change' in stereopsis is defined as a change in stereoacuity of two or more octaves. · 5‐ to 8‐year‐old children with amblyopia

The review found no eligible studies for this question.

1 finding from 1 review