What do systematic reviews say?

Summary of findings: Proteolytic enzymes vs placebo or control

The review found no eligible studies for this question.

• Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary pelvic… 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings: Proteolytic enzymes vs placebo or control

Summary of findings: Proteolytic enzymes may leads to lower acute and late GI toxicity (grade 2+) compared with control (placebo or no intervention) (low certainty).

• Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary pelvic… 2018 · Cochrane Headline outcomes only
  RR 0.45 [0.24, 0.88]
  1 study · 120 participants
  Low

Summary of findings: Proteolytic enzymes vs placebo or control

It is very uncertain whether summary of findings: Proteolytic enzymes changes diarrhoea (grade 2+) compared with control (placebo or no intervention) (very low certainty).

• Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary pelvic… 2018 · Cochrane Headline outcomes only
  RR 1.6 [0.89, 2.89]
  1 study · 56 participants
  Very low

Summary of findings: Proteolytic enzymes vs placebo or control

The review found no eligible studies for this question.

• Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary pelvic… 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings: Protein supplements vs no intervention

The review found no eligible studies for this question.

• Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary pelvic… 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings: Protein supplements vs no intervention

The review found no eligible studies for this question.

• Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary pelvic… 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings: Protein supplements vs no intervention

It is very uncertain whether summary of findings: Protein supplements changes diarrhoea (grade 2+) compared with no intervention (very low certainty).

• Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary pelvic… 2018 · Cochrane Headline outcomes only
  RR 0.53 [0.27, 1.03]
  1 study · 74 participants
  Very low

Summary of findings: Protein supplements vs no intervention

The review found no eligible studies for this question.

• Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary pelvic… 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Superoxide dismutase (SOD) vs no intervention

The review found no eligible studies for this question.

• Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary pelvic… 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Superoxide dismutase (SOD) vs no intervention

Summary of findings: Superoxide dismutase may leads to lower acute and late GI toxicity (grade 2+) compared with no intervention (low certainty).

• Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary pelvic… 2018 · Cochrane Headline outcomes only
  RR 0.2 [0.05, 0.86]
  1 study · 92 participants
  Low

Superoxide dismutase (SOD) vs no intervention

The review found no eligible studies for this question.

• Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary pelvic… 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Superoxide dismutase (SOD) vs no intervention

The review found no eligible studies for this question.

• Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary pelvic… 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings ‐ computerised learning vs no intervention

• Psychological interventions for people with hemophilia 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 17 participants
  Very low

Summary of findings ‐ computerised learning vs no intervention

The review found no eligible studies for this question.

• Psychological interventions for people with hemophilia 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings ‐ computerised learning vs no intervention

The review found no eligible studies for this question.

• Psychological interventions for people with hemophilia 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings ‐ computerised learning vs no intervention

• Psychological interventions for people with hemophilia 2020 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 87 participants
  Very low

Summary of findings ‐ computerised learning vs no intervention

• Psychological interventions for people with hemophilia 2020 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 47 participants
  Low

Summary of findings: Bile acid sequestrants vs no intervention

It is very uncertain whether summary of findings: Bile acid sequestrants changes mean GI symptom scores (during RT) compared with no intervention (very low certainty).

• Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary pelvic… 2018 · Cochrane Headline outcomes only
  MD 0.5
  1 study · 33 participants
  Very low

Summary of findings: Bile acid sequestrants vs no intervention

Summary of findings: Bile acid sequestrants may leads to higher acute and late GI toxicity (grade 2+) compared with no intervention (low certainty).

• Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary pelvic… 2018 · Cochrane Headline outcomes only
  RR 4.24 [1.07, 16.7]
  1 study · 33 participants
  Low

Summary of findings: Bile acid sequestrants vs no intervention

It is very uncertain whether summary of findings: Bile acid sequestrants changes diarrhoea (grade 2+) compared with no intervention (very low certainty).

• Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary pelvic… 2018 · Cochrane Headline outcomes only
  RR 2.82 [0.66, 12.01]
  1 study · 33 participants
  Very low