Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,103 questions · 1,157 findings · 177 reviews · Headline outcomes only

No studies found 291 · 25.2%GRADE not reported 85 · 7.3%Very low 317 · 27.4%Low 258 · 22.3%Moderate 169 · 14.6%High 37 · 3.2%

Platelet‐rich plasma gel vs absorbent sterile cotton gauze

Proportion of wounds healed · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease

The review found no eligible studies for this question.

3 findings from 1 review

Platelet‐rich plasma gel vs absorbent sterile cotton gauze

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease

The review found no eligible studies for this question.

1 finding from 1 review

Gentamicin‐impregnated collagen sponge vs no dressing

Time to complete healing · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease

It is very uncertain whether gentamicin‐impregnated collagen sponge changes time to wound healing (days) compared with no dressing (very low certainty).

1 finding from 1 review

Gentamicin‐impregnated collagen sponge vs no dressing

Proportion of wounds healed · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease

The review found no eligible studies for this question.

3 findings from 1 review

Gentamicin‐impregnated collagen sponge vs no dressing

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease

The review found no eligible studies for this question.

1 finding from 1 review

Dialkylcarbamoyl chloride (DACC)‐coated dressing vs alginate dressing

Proportion of wounds healed · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease

It is very uncertain whether dialkylcarbamoyl chloride (DACC)‐coated dressing changes proportion of wounds healed at 25 days compared with alginate dressing (very low certainty).

3 findings from 1 review

Dialkylcarbamoyl chloride (DACC)‐coated dressing vs alginate dressing

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease

The review found no eligible studies for this question.

1 finding from 1 review

Dialkylcarbamoyl chloride (DACC)‐coated dressing vs alginate dressing

Adverse effects (surgical site infection or allergic reaction) · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease

The review found no eligible studies for this question.

1 finding from 1 review

Timing of wound closure (immediate vs delayed)

Deep surgical site infection · adults with open long bone fractures of the upper and lower limbs

It is very uncertain whether timing of wound closure (immediate changes deep surgical site infection compared with delayed) (very low certainty).

1 finding from 1 review

Timing of wound closure (immediate vs delayed)

Delayed or non‐union (medium term) · adults with open long bone fractures of the upper and lower limbs

It is very uncertain whether timing of wound closure (immediate changes delayed union or non‐union compared with delayed) (very low certainty).

1 finding from 1 review

Timing of wound closure (immediate vs delayed)

Adverse events ‐ superficial infection · adults with open long bone fractures of the upper and lower limbs

It is very uncertain whether timing of wound closure (immediate changes adverse events ‐ superficial infection compared with delayed) (very low certainty).

1 finding from 1 review