Findings

What do systematic reviews say?

1,310 questions · 1,358 findings · 214 reviews

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No studies found 230 · 16.9%GRADE not reported 169 · 12.4%Very low 269 · 19.8%Low 277 · 20.4%Moderate 291 · 21.4%High 122 · 9%

Summary of findings: complete control of vomiting during the overall phase (MEC) when vs treatment with granisetron

Palonosetron (0 RCTs; 0 participants) · adult cancer patients at risk for CINV caused by moderately emetogenic chemotherapy

1 finding from 1 review

Antiemetics for adults for prevention of nausea and vomiting caused by moderately or highly emetogenic chemotherapy: a… 2021 · Cochrane Headline outcomes only
no estimate extracted
22 studies · 7800 participants
Low

Summary of findings: complete control of vomiting during the overall phase (MEC) when vs treatment with granisetron

aprepitant + granisetron · adult cancer patients at risk for CINV caused by moderately emetogenic chemotherapy

1 finding from 1 review

Antiemetics for adults for prevention of nausea and vomiting caused by moderately or highly emetogenic chemotherapy: a… 2021 · Cochrane Headline outcomes only
no estimate extracted
22 studies · 7800 participants
Low

Summary of findings: complete control of vomiting during the overall phase (MEC) when vs treatment with granisetron

azasetron · adult cancer patients at risk for CINV caused by moderately emetogenic chemotherapy

1 finding from 1 review

Antiemetics for adults for prevention of nausea and vomiting caused by moderately or highly emetogenic chemotherapy: a… 2021 · Cochrane Headline outcomes only
no estimate extracted
22 studies · 7800 participants
Low

Summary of findings: complete control of vomiting during the overall phase (MEC) when vs treatment with granisetron

fosaprepitant + ondansetron · adult cancer patients at risk for CINV caused by moderately emetogenic chemotherapy

1 finding from 1 review

Antiemetics for adults for prevention of nausea and vomiting caused by moderately or highly emetogenic chemotherapy: a… 2021 · Cochrane Headline outcomes only
no estimate extracted
22 studies · 7800 participants
Low

Summary of findings: complete control of vomiting during the overall phase (MEC) when vs treatment with granisetron

aprepitant + ondansetron · adult cancer patients at risk for CINV caused by moderately emetogenic chemotherapy

1 finding from 1 review

Antiemetics for adults for prevention of nausea and vomiting caused by moderately or highly emetogenic chemotherapy: a… 2021 · Cochrane Headline outcomes only
no estimate extracted
22 studies · 7800 participants
Low

Summary of findings: complete control of vomiting during the overall phase (MEC) when vs treatment with granisetron

casopitant + ondansetron · adult cancer patients at risk for CINV caused by moderately emetogenic chemotherapy

1 finding from 1 review

Antiemetics for adults for prevention of nausea and vomiting caused by moderately or highly emetogenic chemotherapy: a… 2021 · Cochrane Headline outcomes only
no estimate extracted
22 studies · 7800 participants
Low

Summary of findings: complete control of vomiting during the overall phase (MEC) when vs treatment with granisetron

ondansetron · adult cancer patients at risk for CINV caused by moderately emetogenic chemotherapy

1 finding from 1 review

Antiemetics for adults for prevention of nausea and vomiting caused by moderately or highly emetogenic chemotherapy: a… 2021 · Cochrane Headline outcomes only
no estimate extracted
22 studies · 7800 participants
Low

Summary of findings: serious adverse events (MEC) when vs treatment with granisetron

Interventions (corticosteroids included in all regimens)a · adult cancer patients at risk for CINV caused by moderately emetogenic chemotherapy

The review found no eligible studies for this question.

1 finding from 1 review

Antiemetics for adults for prevention of nausea and vomiting caused by moderately or highly emetogenic chemotherapy: a… 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings: serious adverse events (MEC) when vs treatment with granisetron

rolapitant + granisetron · adult cancer patients at risk for CINV caused by moderately emetogenic chemotherapy

1 finding from 1 review

Antiemetics for adults for prevention of nausea and vomiting caused by moderately or highly emetogenic chemotherapy: a… 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 1344 participants
Low

Surgical interventions (exploration and decompression / external neurolysis, internal neurolysis, neurorrhaphy / direct repair, neuroma excision, anastomosis, autologous or allograft nerve grafting or tubulization) vs non‐surgical treatment

Quality of life · Adults with symptomatic mild to moderate knee osteoarthritis defined as knee pain and radiographic evidence of non‐end stage…

The review found no eligible studies for this question.

1 finding from 1 review

Surgical interventions for symptomatic mild to moderate knee osteoarthritis 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Cognitive training vs control immediately post intervention

Change in a global measure of cognition (composite) · people with mild to moderate dementia

2 findings from 1 review

Cognitive training for people with mild to moderate dementia 2019 · Cochrane Headline outcomes only
no estimate extracted
27 studies · 1389 participants
Moderate
Cognitive training for people with mild to moderate dementia 2019 · Cochrane Headline outcomes only
no estimate extracted
20 studies · 1288 participants
Low

Cognitive training vs control

Change in disease progression · people with mild to moderate dementia

1 finding from 1 review

Cognitive training for people with mild to moderate dementia 2019 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 98 participants
Very low

Cognitive training vs control

Change in delayed memory · people with mild to moderate dementia

1 finding from 1 review

Cognitive training for people with mild to moderate dementia 2019 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 253 participants
Very low

Cognitive training vs control

Change in capacity for activities of daily living · people with mild to moderate dementia

1 finding from 1 review

Cognitive training for people with mild to moderate dementia 2019 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 64 participants
Low

Cognitive training vs control

Mood · people with mild to moderate dementia

1 finding from 1 review

Cognitive training for people with mild to moderate dementia 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 30 participants
Low

Cognitive training vs control

Change in mood and well‐being (caregiver) · people with mild to moderate dementia

1 finding from 1 review

Cognitive training for people with mild to moderate dementia 2019 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Cognitive training vs alternative treatment immediately post intervention

Change in a global measure of cognition (composite) · people with mild to moderate dementia

2 findings from 1 review

Cognitive training for people with mild to moderate dementia 2019 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 769 participants
Low
Cognitive training for people with mild to moderate dementia 2019 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 724 participants
Very low

Cognitive training vs alternative treatment immediately post intervention

Change in delayed memory · people with mild to moderate dementia

1 finding from 1 review

Cognitive training for people with mild to moderate dementia 2019 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 147 participants
Very low

Cognitive training vs alternative treatment immediately post intervention

Mood · people with mild to moderate dementia

1 finding from 1 review

Cognitive training for people with mild to moderate dementia 2019 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 543 participants
Moderate

Cognitive training vs alternative treatment immediately post intervention

Change in capacity for activities of daily living · people with mild to moderate dementia

1 finding from 1 review

Cognitive training for people with mild to moderate dementia 2019 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 525 participants
Moderate