Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

471 questions · 478 findings · 111 reviews

No studies found 68 · 14.2%GRADE not reported 42 · 8.8%Very low 143 · 29.9%Low 133 · 27.8%Moderate 73 · 15.3%High 19 · 4%

Discontinuing cholinesterase inhibitor vs continued cholinesterase inhibitor

Cognitive function · people with dementia
2 findings from 1 review

Discontinuing cholinesterase inhibitor vs continued cholinesterase inhibitor

Dropout due to lack of efficacy of trial medication or deterioration in overall medical condition · people with dementia

Discontinuing cholinesterase inhibitor showed no clear difference in dropout due to lack of efficacy of trial medication or deterioration… compared with continued cholinesterase inhibitor (low certainty).

1 finding from 1 review

Discontinuing cholinesterase inhibitor vs continued cholinesterase inhibitor

Change in NPI · people with dementia
2 findings from 1 review

Reminders (+/‐ educational information) vs usual family planning care

Adherence to method use as indicated by on‐time injections overall · Women of reproductive age seeking to avoid pregnancy

Reminders (+/‐ educational information) showed no clear difference in adherence to method use as indicated by on‐time injections overall compared with usual family planning care (low certainty).

1 finding from 1 review

Physical breastfeeding support interventions (electric or manual breast pump) vs usual care (no pump)

Non‐initiation of breastfeeding · women with a pre‐pregnancy BMI > 29 kg/m², who were intending to breastfeed, had no history of breast surgery, who were at least 19 years…

The review found no eligible studies for this question.

1 finding from 1 review

Multiple methods of breastfeeding support (including social, educational and/or physical support) vs usual care

Breastfeeding · pregnant or lactating women who were overweight or obese

It is very uncertain whether multiple methods of breastfeeding support (including social,… changes any breastfeeding at 6 months compared with usual care (very low certainty).

2 findings from 1 review

Physical breastfeeding support interventions (electric or manual breast pump) vs usual care (no pump)

Exclusive breastfeeding at 4‐6 weeks · women with a pre‐pregnancy BMI > 29 kg/m², who were intending to breastfeed, had no history of breast surgery, who were at least 19 years…

It is very uncertain whether physical breastfeeding support interventions (electric or manual… changes exclusive breastfeeding at 4‐6 weeks compared with usual care (no pump) (very low certainty).

1 finding from 1 review

Physical breastfeeding support interventions (electric or manual breast pump) vs usual care (no pump)

Breastfeeding · women with a pre‐pregnancy BMI > 29 kg/m², who were intending to breastfeed, had no history of breast surgery, who were at least 19 years…

It is very uncertain whether physical breastfeeding support interventions (electric or manual… changes any breastfeeding at 4‐6 weeks compared with usual care (no pump) (very low certainty).

2 findings from 1 review