Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

509 questions · 521 findings · 45 reviews

No studies found 87 · 16.7%GRADE not reported 61 · 11.7%Very low 166 · 31.9%Low 120 · 23%Moderate 73 · 14%High 14 · 2.7%

FLUPHENAZINE (ORAL) vs AMISULPRIDE

Adverse effects: Extrapyramidal effects ‐ concomitant anticholinergic medication ‐ short term (up to 12 weeks) Participants requiring concomitant anticholinergic medication · patients with schizophrenia

It is very uncertain whether FLUPHENAZINE (ORAL) changes adverse effects: Extrapyramidal effects ‐ concomitant… compared with AMISULPRIDE (very low certainty).

1 finding from 1 review

FLUPHENAZINE (ORAL) vs RISPERIDONE

Clinically important response (defined by study) ‐ short term (up to 12 weeks) decreased rate of BPRS score < 20% · patients with schizophrenia

It is very uncertain whether FLUPHENAZINE (ORAL) changes clinically important response (defined by study) ‐ short term (up to… compared with RISPERIDONE (very low certainty).

1 finding from 1 review

Intervention not reported

At least 50 % pain relief · adults with fibromyalgia
1 finding from 1 review

Intervention not reported

Patient Global Impression of Change much or very much improved · adults with fibromyalgia

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Sleep problems (Scale 0 to 21; higher scores indicate more sleep problems) · adults with fibromyalgia
1 finding from 1 review

Intervention not reported

Depression (Scale 0 to 50) · adults with fibromyalgia
1 finding from 1 review

Intervention not reported

Withdrawals due to adverse events · adults with fibromyalgia
1 finding from 1 review

Intervention not reported

Serious adverse events · adults with fibromyalgia
1 finding from 1 review

Intervention not reported

Substantial weight gain · adults with fibromyalgia
1 finding from 1 review