Gynaecomastia · people with chronic kidney disease requiring dialysis
Aldosterone antagonists (spironolactone or eplerenone) probably leads to higher gynaecomastia compared with control (placebo or standard care) (moderate certainty).
1 finding from 1 review
Left ventricular mass · people with chronic kidney disease requiring dialysis
1 finding from 1 review
Failure of PDA closure within 1 week of administration of the first dose of indomethacin · symptomatic patent ductus arteriosus in preterm infants
Indomethacin leads to lower failure of PDA closure within 1 week of administration of the first… compared with placebo or control (high certainty).
1 finding from 1 review
Bronchopulmonary dysplasia at 28 days · symptomatic patent ductus arteriosus in preterm infants
Indomethacin showed no clear difference in bronchopulmonary dysplasia at 28 days compared with placebo or control (low certainty).
1 finding from 1 review
Bronchopulmonary dysplasia · symptomatic patent ductus arteriosus in preterm infants
Indomethacin showed no clear difference in bronchopulmonary dysplasia at 36 weeks' gestation compared with placebo or control (low certainty).
1 finding from 1 review
All‐cause neonatal mortality before hospital discharge · symptomatic patent ductus arteriosus in preterm infants
Indomethacin showed no clear difference in all‐cause neonatal mortality before hospital discharge compared with placebo or control (moderate certainty).
1 finding from 1 review
Proportion of infants requiring surgical ligation of PDA · symptomatic patent ductus arteriosus in preterm infants
Indomethacin showed no clear difference in proportion of infants requiring surgical ligation of PDA compared with placebo or control (moderate certainty).
1 finding from 1 review
NEC ≥ stage II · symptomatic patent ductus arteriosus in preterm infants
Indomethacin showed no clear difference in NEC (≥ Bell stage 2) compared with placebo or control (low certainty).
1 finding from 1 review
Mucocutaneous or gastrointestinal bleeding · symptomatic patent ductus arteriosus in preterm infants
Indomethacin showed no clear difference in mucocutaneous or gastrointestinal bleeding compared with placebo or control (low certainty).
1 finding from 1 review
Incidence of pneumonia Defined as patient admitted to hospital with a diagnosis of pneumonia Dose: 2 g per day · school‐aged children (6 to 15 years) and marine corps recruits (mean age 18.5 years)
It is very uncertain whether vitamin C changes incidence of pneumonia Defined as patient admitted to hospital with… compared with placebo (very low certainty).
1 finding from 1 review
Prevalance of pneumonia · school‐aged children (6 to 15 years) and marine corps recruits (mean age 18.5 years)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Mortality (pneumonia-associated) · school‐aged children (6 to 15 years) and marine corps recruits (mean age 18.5 years)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse effects (urticaria) Defined as participants reporting urticaria (hives) Dose: 2 g per day · school‐aged children (6 to 15 years) and marine corps recruits (mean age 18.5 years)
It is very uncertain whether vitamin C changes adverse effects (urticaria) Defined as participants reporting… compared with placebo (very low certainty).
1 finding from 1 review
Duration of illness · children under 5 years of age
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Clinical cure · children under 5 years of age
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Mortality (pneumonia-associated) · children under 5 years of age
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse effects · children under 5 years of age
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Seizure freedom · women with seizures due to catamenial epilepsy
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Withdrawals due to any reason · women with seizures due to catamenial epilepsy
Progesterone showed no clear difference in number of withdrawals from the study: for any reason compared with placebo (moderate certainty).
1 finding from 1 review
Adverse events: any adverse event · women with seizures due to catamenial epilepsy
Progesterone showed no clear difference in adverse events: any adverse event compared with placebo (moderate certainty).
1 finding from 1 review