Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,771 questions · 10,185 findings · 893 reviews

No studies found 2,109 · 20.7%GRADE not reported 1,125 · 11%Very low 2,279 · 22.4%Low 2,514 · 24.7%Moderate 1,709 · 16.8%High 449 · 4.4%

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Botulinum toxin type A vs placebo

Subjective participant assessment at 4 weeks; 755 participants(6 RCTs) · cervical dystonia

Botulinum toxin type A leads to higher subjective participant assessment at 4 weeks; 755 participants(6 RCTs) compared with placebo (high certainty).

1 finding from 1 review

Botulinum toxin type A vs placebo

Tolerability assessed as dropouts at 4 to 6 weeks: 705 participants (5 RCTs) · cervical dystonia

Botulinum toxin type A leads to lower tolerability assessed as dropouts at 4 to 6 weeks: 705 participants… compared with placebo (high certainty).

1 finding from 1 review

HALOPERIDOL vs placebo

Symptoms of delirium within 24 hoursa · terminally ill adults with delirium

Summary of findings: haloperidol showed no clear difference in symptoms of delirium within 24 hoursa compared with placebo (low certainty).

1 finding from 1 review

HALOPERIDOL vs OLANZAPINE

Symptoms of delirium within 24 hoursa · terminally ill adults with delirium

It is very uncertain whether summary of findings: haloperidol changes symptoms of delirium within 24 hoursa compared with olanzapine (very low certainty).

1 finding from 1 review

HALOPERIDOL vs OLANZAPINE

Symptoms of delirium between 24 and 48 hoursa · terminally ill adults with delirium

It is very uncertain whether summary of findings: haloperidol changes symptoms of delirium between 24 and 48 hoursa compared with olanzapine (very low certainty).

1 finding from 1 review

RISPERIDONE vs placebo

Symptoms of delirium within 24 hoursa · terminally ill adults with delirium

Summary of findings: risperidone showed no clear difference in symptoms of delirium within 24 hoursa compared with placebo (low certainty).

1 finding from 1 review

RISPERIDONE vs placebo

Symptoms of delirium between 24 and 48 hoursa · terminally ill adults with delirium

Summary of findings: risperidone showed no clear difference in symptoms of delirium between 24 and 48 hoursa compared with placebo (low certainty).

1 finding from 1 review

HALOPERIDOL vs placebo

Symptoms of delirium between 24 and 48 hoursa · terminally ill adults with delirium

Summary of findings: haloperidol showed no clear difference in symptoms of delirium between 24 and 48 hoursa compared with placebo (low certainty).

1 finding from 1 review