Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,815 questions · 6,211 findings · 638 reviews · Headline outcomes only

No studies found 1,052 · 16.9%GRADE not reported 441 · 7.1%Very low 1,700 · 27.4%Low 1,651 · 26.6%Moderate 1,070 · 17.2%High 297 · 4.8%

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Any systemic treatment vs placebo

Secukinumab · people with chronic plaque psoriasis

Any systemic treatment showed no clear difference in secukinumab compared with placebo (moderate certainty).

2 findings from 1 review

Mitomycin C dacryocystorhinostomy vs dacryocystorhinostomy alone

Functional success, defined as the relief of epiphora · nasolacrimal duct obstruction

Mitomycin C dacryocystorhinostomy showed no clear difference in functional success, defined as the relief of epiphora compared with dacryocystorhinostomy alone (low certainty).

2 findings from 1 review

Mitomycin C dacryocystorhinostomy vs dacryocystorhinostomy alone

Anatomic success, defined as patency to lacrimal irrigation · nasolacrimal duct obstruction

Mitomycin C dacryocystorhinostomy showed no clear difference in anatomic success, defined as patency to lacrimal irrigation compared with dacryocystorhinostomy alone (low certainty).

2 findings from 1 review

Mitomycin C dacryocystorhinostomy vs dacryocystorhinostomy alone

Ostium size on nasal endoscopy · nasolacrimal duct obstruction

Mitomycin C dacryocystorhinostomy showed no clear difference in ostium size on nasal endoscopy compared with dacryocystorhinostomy alone (low certainty).

2 findings from 1 review

Primary objective: mobile stock notification with enhanced management vs usual care

Proportion of healthcare workers who reported a stockout of drugs in the last 30 days (stockout of cotrimoxazole to treat bacterial infections) · healthcare workers and other health professionals involved in commodity and stock management

It is very uncertain whether primary objective: mobile stock notification with enhanced management changes proportion of healthcare workers who reported a stockout of drugs in… compared with standard care (very low certainty).

1 finding from 1 review

Primary objective: mobile stock notification with effective product transport vs usual care

Proportion of healthcare workers who reported a stockout of drugs in the last 30 days (stockout of cotrimoxazole to treat bacterial infections) · healthcare workers and other health professionals involved in commodity and stock management

It is very uncertain whether primary objective: mobile stock notification with effective product… changes proportion of healthcare workers who reported a stockout of drugs in… compared with standard care (very low certainty).

1 finding from 1 review

Primary objective: mobile stock notification with effective product transport vs usual care

Proportion of healthcare workers who reported a stockout of drugs in the last 30 days (stockout of oral rehydration salts (ORS) to treat dehydration) · healthcare workers and other health professionals involved in commodity and stock management

It is very uncertain whether primary objective: mobile stock notification with effective product… changes proportion of healthcare workers who reported a stockout of drugs in… compared with standard care (very low certainty).

1 finding from 1 review

Primary objective: mobile stock notification with effective product transport vs usual care

Proportion of healthcare workers who reported a stockout of drugs in the last 30 days (stockout of zinc 20 mg to treat diarrhoea) · healthcare workers and other health professionals involved in commodity and stock management

It is very uncertain whether primary objective: mobile stock notification with effective product… changes proportion of healthcare workers who reported a stockout of drugs in… compared with standard care (very low certainty).

1 finding from 1 review

Primary objective: mobile stock notification with effective product transport vs usual care

Quality of data about stock management (assessed by the extent to which HSAs (intervention group participants) send messages about the stocks on hand for all the products they managed) · healthcare workers and other health professionals involved in commodity and stock management
1 finding from 1 review

Primary objective: mobile stock notification with effective product transport vs usual care

Time between stock‐level reporting and appropriate action (measured over an 18‐month period (January 2012 to June 2013) · healthcare workers and other health professionals involved in commodity and stock management
1 finding from 1 review

Primary objective: mobile stock notification with effective product transport vs usual care

Provider acceptability and satisfaction (Proportion of participants who reported using the digital intervention) · healthcare workers and other health professionals involved in commodity and stock management
1 finding from 1 review

Primary objective: mobile stock notification with effective product transport vs usual care

Unintended consequences · healthcare workers and other health professionals involved in commodity and stock management

The review found no eligible studies for this question.

1 finding from 1 review

Primary objective: mobile stock notification with enhanced management vs usual care

Proportion of healthcare workers who reported a stockout of drugs in the last 30 days (stockout of oral rehydration salts (ORS) to treat dehydration) · healthcare workers and other health professionals involved in commodity and stock management

It is very uncertain whether primary objective: mobile stock notification with enhanced management changes proportion of healthcare workers who reported a stockout of drugs in… compared with standard care (very low certainty).

1 finding from 1 review

Primary objective: mobile stock notification with enhanced management vs usual care

Proportion of healthcare workers who reported a stockout of drugs in the last 30 days (stockout of zinc 20 mg to treat diarrhoea) · healthcare workers and other health professionals involved in commodity and stock management

It is very uncertain whether primary objective: mobile stock notification with enhanced management changes proportion of healthcare workers who reported a stockout of drugs in… compared with standard care (very low certainty).

1 finding from 1 review