Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,760 questions · 8,065 findings · 1,036 reviews

No studies found 1,686 · 20.9%GRADE not reported 675 · 8.4%Very low 1,953 · 24.2%Low 2,048 · 25.4%Moderate 1,296 · 16.1%High 407 · 5%

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Systemic antibiotic prophylaxis (any regimen; topical therapy excluded) administered before and/or after tooth extraction vs Placebo

Outcome not reported · Immunosuppressed / immunocompromised patients (e.g. HIV infection, AIDS, diabetes, transplants) undergoing tooth extraction

The review found no eligible studies for this question.

1 finding from 1 review

Systemic antibiotic prophylaxis (any regimen; topical therapy excluded) administered before and/or after tooth extraction vs placebo

Fever · People undergoing tooth extraction (21 of 23 trials: healthy patients undergoing impacted third molar extraction; 1 routine intra-alveolar…

It is very uncertain whether systemic antibiotic prophylaxis (any regimen; topical therapy… changes fever (6th-7th day) compared with placebo (very low certainty).

1 finding from 1 review

Systemic antibiotic prophylaxis (any regimen; topical therapy excluded) administered before and/or after tooth extraction vs Placebo

Outcome not reported · Patients undergoing tooth extraction for severe dental caries or periodontal disease in general dental practice (non-third-molar / decayed…

The review found no eligible studies for this question.

1 finding from 1 review
  • No studies in general dental practice for removal of decayed teeth. PUB3 added one routine intra-alveolar extraction trial and one complex oral surgery trial (2 of 23 non-third-molar), but the single intra-alveolar…
    0 studies
    No studies found

Intervention not reported

Protein energy wasting (malnutrition) · non‐diabetic adults with CKD

The intervention showed no clear difference in protein energy wasting (malnutrition) (low certainty).

1 finding from 1 review

Intervention not reported

Serum/plasma creatinine levels (μmol/L) after treatment Normal values for male and female newborns 17.7 to 88.4 µmol/L · preterm infants with patent ductus arteriosus

The intervention showed no clear difference in serum/plasma creatinine levels (μmol/L) after treatment Normal… (low certainty).

1 finding from 1 review

Intervention not reported

Failure to close a patent ductus arteriosus after 3 doses of ibuprofen · preterm infants with patent ductus arteriosus

The intervention probably leads to lower failure to close a patent ductus arteriosus after 3 doses of ibuprofen (moderate certainty).

1 finding from 1 review

Intervention not reported

Failure to close a patent ductus arteriosus (PDA) (after single or 3 doses) · preterm infants with patent ductus arteriosus

The intervention showed no clear difference in failure to close a patent ductus arteriosus (PDA) (after single or 3… (moderate certainty).

1 finding from 1 review