Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

4,320 questions · 4,561 findings · 388 reviews

No studies found 1,138 · 25%GRADE not reported 886 · 19.4%Very low 1,014 · 22.2%Low 849 · 18.6%Moderate 543 · 11.9%High 131 · 2.9%

Fluoride toothpaste vs Non-fluoride (0 ppm F) placebo toothpaste

Proportion developing new caries · Children and adolescents aged 16 years or less

Fluoride toothpaste showed no clear difference in proportion of children developing one or more new caries compared with placebo (non-fluoride) toothpaste; GRADE not reported.

1 finding from 1 review

Fluoride toothpaste vs Non-fluoride (0 ppm F) placebo toothpaste

Acquiring extrinsic tooth staining (adverse effect; stannous fluoride toothpaste) · Children and adolescents aged 16 years or less

Fluoride toothpaste led to higher acquiring extrinsic tooth staining (adverse effect; stannous… compared with placebo (non-fluoride) toothpaste; GRADE not reported.

1 finding from 1 review

Synbiotic vs placebo

Severity of pain (at study end, using the Faces Pain Scale) · children (4 to 18 years) with functional abdominal pain disorders

It is very uncertain whether synbiotic changes severity of pain (at study end, using the Faces Pain Scale) compared with placebo (very low certainty).

1 finding from 1 review