Findings

What do systematic reviews say?

4,695 questions · 4,979 findings · 433 reviews

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No studies found 998 · 20%GRADE not reported 1,140 · 22.9%Very low 1,024 · 20.6%Low 1,029 · 20.7%Moderate 636 · 12.8%High 152 · 3.1%

Ketoprofen 50 mg vs placebo

Participants with a serious adverse event following a single dose · adults with moderate or severe acute postoperative pain

1 finding from 1 review

Single dose oral ketoprofen or dexketoprofen for acute postoperative pain in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 688 participants
Very low

Dexketoprofen 10 mg‐12.5 mg vs placebo

At least 50% of maximum pain relief over 4 to 6 hours · adults with moderate or severe acute postoperative pain

1 finding from 1 review

Single dose oral ketoprofen or dexketoprofen for acute postoperative pain in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 480 participants
High

Dexketoprofen 10 mg‐12.5 mg vs placebo

Median (mean) time to use of rescue medication · adults with moderate or severe acute postoperative pain

1 finding from 1 review

Single dose oral ketoprofen or dexketoprofen for acute postoperative pain in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 122 participants
Very low

Dexketoprofen 10 mg‐12.5 mg vs placebo

Number of women requiring rescue medication · adults with moderate or severe acute postoperative pain

1 finding from 1 review

Single dose oral ketoprofen or dexketoprofen for acute postoperative pain in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 373 participants
High

Dexketoprofen 10 mg‐12.5 mg vs placebo

Participants with ≥ 1 adverse event following a single dose · adults with moderate or severe acute postoperative pain

1 finding from 1 review

Single dose oral ketoprofen or dexketoprofen for acute postoperative pain in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 380 participants
High

Dexketoprofen 10 mg‐12.5 mg vs placebo

Participants with a serious adverse event following a single dose · adults with moderate or severe acute postoperative pain

1 finding from 1 review

Single dose oral ketoprofen or dexketoprofen for acute postoperative pain in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 574 participants
Very low

Dexketoprofen 20 mg or 25 mg vs placebo

At least 50% of maximum pain relief over 4 to 6 hours · adults with moderate or severe acute postoperative pain

1 finding from 1 review

Single dose oral ketoprofen or dexketoprofen for acute postoperative pain in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 1177 participants
High

Dexketoprofen 20 mg or 25 mg vs placebo

Median (mean) time to use of rescue medication · adults with moderate or severe acute postoperative pain

1 finding from 1 review

Single dose oral ketoprofen or dexketoprofen for acute postoperative pain in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 281 participants
Very low

Dexketoprofen 20 mg or 25 mg vs placebo

Number of women requiring rescue medication · adults with moderate or severe acute postoperative pain

1 finding from 1 review

Single dose oral ketoprofen or dexketoprofen for acute postoperative pain in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 445 participants
High

Dexketoprofen 20 mg or 25 mg vs placebo

Participants with ≥ 1 adverse event following a single dose · adults with moderate or severe acute postoperative pain

1 finding from 1 review

Single dose oral ketoprofen or dexketoprofen for acute postoperative pain in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 536 participants
High

Ketoprofen 25 mg vs placebo

Median (mean) time to use of rescue medication · adults with moderate or severe acute postoperative pain

1 finding from 1 review

Single dose oral ketoprofen or dexketoprofen for acute postoperative pain in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 188 participants
Very low

Dexketoprofen 20 mg or 25 mg vs placebo

Participants with a serious adverse event following a single dose · adults with moderate or severe acute postoperative pain

1 finding from 1 review

Single dose oral ketoprofen or dexketoprofen for acute postoperative pain in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 1271 participants
Very low

Ketoprofen 25 mg vs placebo

Number of women requiring rescue medication · adults with moderate or severe acute postoperative pain

1 finding from 1 review

Single dose oral ketoprofen or dexketoprofen for acute postoperative pain in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 402 participants
Moderate

Ketoprofen 25 mg vs placebo

Participants with ≥ 1 adverse event following a single dose · adults with moderate or severe acute postoperative pain

1 finding from 1 review

Single dose oral ketoprofen or dexketoprofen for acute postoperative pain in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 490 participants
High

Ketoprofen 25 mg vs placebo

Participants with a serious adverse event following a single dose · adults with moderate or severe acute postoperative pain

1 finding from 1 review

Single dose oral ketoprofen or dexketoprofen for acute postoperative pain in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 535 participants
Very low

Ketoprofen 50 mg vs placebo

At least 50% of maximum pain relief over 4 to 6 hours · adults with moderate or severe acute postoperative pain

1 finding from 1 review

Single dose oral ketoprofen or dexketoprofen for acute postoperative pain in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 594 participants
High

Ketoprofen 50 mg vs placebo

Median (mean) time to use of rescue medication · adults with moderate or severe acute postoperative pain

1 finding from 1 review

Single dose oral ketoprofen or dexketoprofen for acute postoperative pain in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 77 participants
Very low

Ketoprofen 50 mg vs placebo

Number of women requiring rescue medication · adults with moderate or severe acute postoperative pain

1 finding from 1 review

Single dose oral ketoprofen or dexketoprofen for acute postoperative pain in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 263 participants
High

Ketoprofen 50 mg vs placebo

Participants with ≥ 1 adverse event following a single dose · adults with moderate or severe acute postoperative pain

1 finding from 1 review

Single dose oral ketoprofen or dexketoprofen for acute postoperative pain in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 342 participants
High

Clomiphene citrate or letrozole with or without gonadotropins (with or without midcycle antagonist) vs gonadotropins (with GnRH agonists or midcycle antagonist)

Live birth rate per woman · for controlled ovarian stimulation

Clomiphene citrate or letrozole with or without gonadotropins (with… showed no clear difference in live birth per woman compared with gonadotropins (with GnRH agonists or midcycle antagonist) (low certainty).

1 finding from 1 review

Oral medications including clomiphene citrate or aromatase inhibitors with gonadotropins for controlled ovarian… 2017 · Cochrane Headline outcomes only
RR 0.92 [0.66, 1.27]
4 studies · 493 participants
Low