Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,756 questions · 11,779 findings · 747 reviews · Headline outcomes only

No studies found 3,205 · 27.2%GRADE not reported 628 · 5.3%Very low 3,261 · 27.7%Low 2,913 · 24.7%Moderate 1,453 · 12.3%High 319 · 2.7%

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IVIg vs placebo

Death · adults with renal vasculitis

Intravenous immunoglobulin showed no clear difference in death compared with placebo (low certainty).

1 finding from 1 review

Intervention not reported

Dialysis at one year · adults with renal vasculitis

The intervention may leads to lower dialysis at one year (low certainty).

1 finding from 1 review

IVIg vs placebo

Response at 3 months · adults with renal vasculitis

Intravenous immunoglobulin may leads to higher response at 3 months compared with placebo (low certainty).

1 finding from 1 review

IVIg vs placebo

Relapse at 3 months · adults with renal vasculitis

Intravenous immunoglobulin showed no clear difference in relapse at 3 months compared with placebo (low certainty).

1 finding from 1 review

IVIg vs placebo

Adverse events · adults with renal vasculitis

Intravenous immunoglobulin may leads to higher adverse events compared with placebo (low certainty).

1 finding from 1 review

Intervention not reported

Sustained remission · adults with renal vasculitis

The intervention may leads to higher sustained remission (low certainty).

1 finding from 1 review

Intervention not reported

Relapse · adults with renal vasculitis

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Total number of adverse events · adults with renal vasculitis

The intervention showed no clear difference in total number of adverse events (low certainty).

1 finding from 1 review

Intervention not reported

Serious infections · adults with renal vasculitis

The intervention may leads to higher serious infections (low certainty).

1 finding from 1 review

Mohs micrographic surgery vs surgical excision

Recurrence · adults with basal cell carcinoma of the skin

Mohs micrographic surgery showed no clear difference in recurrence at 3 years compared with surgical excision (low certainty).

2 findings from 1 review