Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

397 questions · 406 findings · 36 reviews · All outcomes

No studies found 134 · 33%GRADE not reported 184 · 45.3%Very low 59 · 14.5%Low 19 · 4.7%Moderate 10 · 2.5%High 0 · 0%

Infiltration injection LA and intraligamental injection LA (3-arm) vs no treatment

Postoperative anxiety · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…
1 finding from 1 review

Intraligamental injection local anaesthetic vs no treatment

Parental satisfaction · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…

The review found no eligible studies for this question.

1 finding from 1 review

Primary outcome: topical local anaesthetics vs placebo or no treatment

Postoperative anxiety · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…

The review found no eligible studies for this question.

1 finding from 1 review

Infiltration injection local anaesthetic vs no treatment or placebo

Physiological parameters (cardiac/respiratory events; type and volume of GA drug) · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…
1 finding from 1 review

Intraligamental injection local anaesthetic vs no treatment

Participant satisfaction · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…

The review found no eligible studies for this question.

1 finding from 1 review

Hypnosis vs Inhalation sedation with nitrous oxide and oxygen

Completion of treatment · Children aged 10 to 16 years undergoing orthodontic extractions (Braithwaite 2005)

The review found no eligible studies for this question.

1 finding from 1 review
  • Completion of treatment (yes/no) was a protocol-planned primary outcome but was not reported by the included study for this comparison (Braithwaite 2005); one participant in the sedation arm was withdrawn during…
    Studies not reported
    No studies found

Open reduction and fixation vs Closed (conservative) management (no active intervention other than soft diet, analgesics or antibiotics; or intermaxillary/maxillary-mandibular fixation with rigid or elastic traction)

Outcome not reported · Adults, over 18 years of age, with unilateral or bilateral fractures of the mandibular condyles

The review found no eligible studies for this question.

1 finding from 1 review

Hypnosis vs Inhalation sedation with nitrous oxide and oxygen

Measures of behaviour / negative responses during local anaesthesia administration · Children aged 10 to 16 years undergoing orthodontic extractions (Braithwaite 2005)
1 finding from 1 review
  • Hypnosis can control some of the patient's negative responses to dental treatment, such as movement and behaviour, during administration of local anaesthesia. (Braithwaite 2005; single-blind cross-over, 10 patients…
    1 study · 10 participants
    GRADE not reported

Dental fillings (restorations) vs Dental extractions

Outcome not reported · Children aged 12 years or younger with tooth decay involving at least one tooth in the primary dentition, symptomatic or symptom free

The review found no eligible studies for this question.

1 finding from 1 review

Antifibrinolytic agents (tranexamic acid (TXA) or epsilon aminocaproic acid (EACA)) vs Placebo, no intervention, or usual care

Outcome not reported · People on continuous direct oral anticoagulant (DOAC) treatment undergoing oral or dental procedures

The review found no eligible studies for this question.

1 finding from 1 review