Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

462 questions · 474 findings · 56 reviews · Eyes and Vision

No studies found 147 · 31%GRADE not reported 15 · 3.2%Very low 89 · 18.8%Low 157 · 33.1%Moderate 52 · 11%High 14 · 3%

ISBCS vs DSBCS

Total costs per QALY · people with bilateral age‐related cataracts (NRSs)

The review found no eligible studies for this question.

2 findings from 1 review

ISBCS vs DSBCS

BCDVA · people with bilateral age‐related cataracts (NRSs)

The review found no eligible studies for this question.

2 findings from 1 review

ISBCS vs DSBCS

Patient‐reported outcome measures (PROMs) · people with bilateral age‐related cataracts (NRSs)

The review found no eligible studies for this question.

2 findings from 1 review

ISBCS vs DSBCS

Refraction NOT within 1.0 dioptres of target · people with bilateral age‐related cataracts (NRSs)

ISBCS showed no clear difference in refraction NOT within 1.0 dioptres of target compared with DSBCS (moderate certainty).

2 findings from 1 review

Phaco‐AIT vs Phaco‐Trab

Proportion of participants who were medication‐free (not using drops) at 12 months · people with open‐angle glaucoma

It is very uncertain whether phaco‐AIT changes proportion of participants who were medication‐free (not using… compared with phaco‐Trab (very low certainty).

1 finding from 1 review

Wavefront procedures vs conventional procedures

Proportion of eyes with uncorrected visual acuity (UCVA) of 20/20 or better post‐treatment. ‐ 12 months · Adults with refractive errors

Wavefront procedures showed no clear difference in proportion of eyes with uncorrected visual acuity (UCVA) of 20/20 or… compared with conventional procedures (low certainty).

1 finding from 1 review

Wavefront‐optimized procedures vs wavefront‐guided procedures

Eyes within ± 0.5 D of target refraction · Adults with refractive errors

Wavefront‐optimized procedures showed no clear difference in proportion of eyes within ± 0.50 diopters (D) of target refraction… compared with wavefront‐guided procedures (low certainty).

1 finding from 1 review

Wavefront‐guided LASIK vs wavefront‐guided PRK

Proportion of eyes with uncorrected visual acuity (UCVA) of 20/20 or better post‐treatment. ‐ 12 months · Adults with refractive errors

It is very uncertain whether wavefront‐guided LASIK changes proportion of eyes with uncorrected visual acuity (UCVA) of 20/20 or… compared with wavefront‐guided PRK (very low certainty).

1 finding from 1 review

Wavefront‐guided LASIK vs wavefront‐guided PRK

Loss of 1 or more lines of BSCVA at 12 months post treatment · Adults with refractive errors

It is very uncertain whether wavefront‐guided LASIK changes proportion of eyes that had lost 1 or more lines of best… compared with wavefront‐guided PRK (very low certainty).

1 finding from 1 review

Wavefront‐guided LASIK vs wavefront‐guided PRK

Eyes within ± 0.5 D of target refraction · Adults with refractive errors

It is very uncertain whether wavefront‐guided LASIK changes proportion of eyes within ± 0.50 diopters (D) of target refraction… compared with wavefront‐guided PRK (very low certainty).

1 finding from 1 review