Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,692 questions · 2,586 findings · 180 reviews · Dental caries

No studies found 194 · 7.5%GRADE not reported 1,937 · 74.9%Very low 248 · 9.6%Low 136 · 5.3%Moderate 52 · 2%High 19 · 0.7%

Intervention not reported

Dental caries prevalence · Children (<12 years) and adolescents (12-18 years) with type 1 diabetes

The pooled prevalence of dental caries among children and adolescents with type 1 diabetes was 67% (95% CI 0.56 to 0.77), with high heterogeneity (I2=83%); certainty not graded.

1 finding from 1 review

Intervention not reported

Dental caries prevalence · Children (<12 years) and adolescents (12-18 years) with type 1 diabetes

Caries prevalence in the single North American study was 64% (95% CI 0.52 to 0.74); certainty not graded.

1 finding from 1 review

Intervention not reported

Dental caries prevalence · Children (<12 years) and adolescents (12-18 years) with type 1 diabetes

Caries prevalence was lower in those with mean age >10 years at 57% (95% CI 0.45 to 0.68); certainty not graded.

1 finding from 1 review

Intervention not reported

Dental caries prevalence · Children (<12 years) and adolescents (12-18 years) with type 1 diabetes

Caries prevalence was higher in those with mean age <=10 years at 80% (95% CI 0.74 to 0.85); certainty not graded.

1 finding from 1 review

Intervention not reported

Dental caries prevalence · Children (<12 years) and adolescents (12-18 years) with type 1 diabetes

Caries prevalence among those with poor metabolic control was 66% (95% CI 0.43 to 0.83); certainty not graded.

1 finding from 1 review

Intervention not reported

Dental caries prevalence in primary teeth (cavitated lesions) · Children aged 5-6 years in Latin America and the Caribbean

In other Latin American/Caribbean countries, pooled primary-teeth caries prevalence was 70% (95% CI 59-79%), significantly higher than Brazil (p=0.002); certainty not graded.

1 finding from 1 review

Intervention not reported

Dental caries prevalence in permanent teeth (cavitated lesions) · Children aged 11-13 years in Latin America and the Caribbean

In other Latin American/Caribbean countries, pooled permanent-teeth caries prevalence was 64% (95% CI 45-79%), not significantly different from Brazil (p=0.42); certainty not graded.

1 finding from 1 review

Intervention not reported

Dental caries prevalence in primary teeth (cavitated lesions) · Children aged 5-6 years in Latin America and the Caribbean

In Brazil, pooled primary-teeth caries prevalence in 5-6 year-olds was 52% (95% CI 49-54%); certainty not graded.

1 finding from 1 review

Intervention not reported

Dental caries prevalence in primary teeth (cavitated lesions) · Children aged 5-6 years in Latin America and the Caribbean

About 56% of 5-6 year-old children in Latin America and the Caribbean had dental caries in primary teeth (95% CI 52-59%); certainty not graded.

1 finding from 1 review

Intervention not reported

Dental caries prevalence in permanent teeth (cavitated lesions) · Children aged 11-13 years in Latin America and the Caribbean

In Brazil, pooled permanent-teeth caries prevalence in 11-13 year-olds was 56% (95% CI 53-60%), with a significant declining trend over time; certainty not graded.

1 finding from 1 review

Intervention not reported

Dental caries prevalence in permanent teeth (cavitated lesions) · Children aged 11-13 years in Latin America and the Caribbean

About 58% of 11-13 year-old children in Latin America and the Caribbean had dental caries in permanent teeth (95% CI 54-61%); certainty not graded.

1 finding from 1 review

Fluoride gel (topically applied; operator- or self-applied; any fluoride agent/concentration; frequency at least once a year) vs placebo or no treatment

Caries increment on permanent whole teeth (D(M)FT), prevented fraction · Children and adolescents aged 16 years or younger (permanent dentition)
3 findings from 1 review

Chlorhexidine gel (0.12%) vs no treatment

Mutans streptococci prevalence (presence/absence) · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or…

It is very uncertain whether chlorhexidine gel (0.12%) changes mutans streptococci prevalence (presence/absence) compared with no treatment (very low certainty).

1 finding from 1 review

Fluoride gel (topically applied; operator- or self-applied; any fluoride agent/concentration; frequency at least once a year) vs placebo or no treatment

Caries increment on permanent tooth surfaces (D(M)FS), prevented fraction · Children and adolescents aged 16 years or younger (permanent dentition)
3 findings from 1 review

Chlorhexidine gel (0.12%) vs no treatment

Presence of new caries in the primary teeth · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or…

It is very uncertain whether chlorhexidine gel (0.12%) changes presence of new caries in the primary teeth compared with no treatment (very low certainty).

1 finding from 1 review