Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,935 questions · 1,986 findings · 260 reviews · Headline outcomes only

No studies found 503 · 25.3%GRADE not reported 76 · 3.8%Very low 593 · 29.9%Low 509 · 25.6%Moderate 241 · 12.1%High 64 · 3.2%

Interventions to reduce blood loss during myomectomy for fibroids vs placebo or no treatment

Dinoprostone (prostaglandin E2 analogue) · women with uterine fibroids

Interventions to reduce blood loss during myomectomy for fibroids showed no clear difference in dinoprostone (prostaglandin E2 analogue) compared with placebo or no treatment (low certainty).

1 finding from 1 review

Integrated parenting and substance use‐focused component psychosocial interventions vs treatment

Frequency of drug use 12 months · Parents who use substances
2 findings from 1 review

Parenting‐focused psychosocial interventions WITHOUT substance use‐focused component vs treatment

Frequency of drug use 12 months · Parents who use substances
2 findings from 1 review

Beta‐lactam (ceftriaxone) plus aminoglycoside (gentamicin) vs beta‐lactam (ceftriaxone)

Need for cardiac surgical interventions · people with infective endocarditis due to penicillin‐susceptible Streptococci

It is very uncertain whether beta‐lactam (ceftriaxone) plus aminoglycoside (gentamicin) changes need for cardiac surgical interventions compared with beta‐lactam (ceftriaxone) (very low certainty).

1 finding from 1 review

Asthma Clinics (Intervention) vs controls

Number of participants experiencing one or more episodes requiring ED visit · people with asthma

It is very uncertain whether asthma Clinics (Intervention) changes A&E visits Number of people experiencing one or more A&E visit compared with controls (very low certainty).

1 finding from 1 review

Asthma Clinics (Intervention) vs controls

Hospital admissions · people with asthma

Asthma Clinics (Intervention) showed no clear difference in hospital admissions Number of people experiencing one or more… compared with controls (low certainty).

1 finding from 1 review

Monetary incentives vs usual care

Proportion of children who received the vaccine under study (measles/MMR) ‐ household monetary incentivef · children under 5 years of age

It is very uncertain whether monetary incentives changes proportion of children who received the vaccine under study… compared with routine care (very low certainty).

1 finding from 1 review

Monetary incentives vs usual care

Proportion of children who received the vaccine under study (MMR) ‐ service‐level monetary incentiveg · children under 5 years of age

It is very uncertain whether monetary incentives changes proportion of children who received the vaccine under study (MMR) ‐… compared with routine care (very low certainty).

1 finding from 1 review

Monetary incentives vs usual care

Proportion of children who received the vaccine under study (MMR) ‐ household + service‐level monetary incentive · children under 5 years of age

It is very uncertain whether monetary incentives changes proportion of children who received the vaccine under study (MMR) ‐… compared with routine care (very low certainty).

1 finding from 1 review