Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

520 questions · 527 findings · 55 reviews · Headline outcomes only

No studies found 140 · 26.6%GRADE not reported 66 · 12.5%Very low 121 · 23%Low 115 · 21.8%Moderate 77 · 14.6%High 8 · 1.5%

Multi‐component interventions (with telehealth as a component of care) vs usual care

Transmission‐related outcomes: hospitalization ‐ Number or proportion of hospital admissions · patients with chronic obstructive pulmonary disease

Multi‐component interventions (with telehealth as a component of care) showed no clear difference in number of people who had at least 1 hospital admission compared with usual care (low certainty).

1 finding from 1 review

Multi‐component interventions (with telehealth as a component of care) vs usual care

Number of people re‐admitted (all‐cause) · patients with chronic obstructive pulmonary disease

Multi‐component interventions (with telehealth as a component of care) probably leads to lower number of people re‐admitted (all‐cause) compared with usual care (moderate certainty).

1 finding from 1 review

Multi‐component interventions (with telehealth as a component of care) vs usual care

Anti‐cytokine, all‐cause mortality ‐ uncertain risk of bias · patients with chronic obstructive pulmonary disease

It is very uncertain whether multi‐component interventions (with telehealth as a component of care) changes mortality (all‐cause) overall analysis compared with usual care (very low certainty).

1 finding from 1 review

Multi‐component interventions (with telehealth as a component of care) vs usual care

Adverse events: number of people with 1 or more (all‐cause) · patients with chronic obstructive pulmonary disease

It is very uncertain whether multi‐component interventions (with telehealth as a component of care) changes adverse events: number of people with 1 or more (all‐cause) compared with usual care (very low certainty).

1 finding from 1 review

Higher threshold (500 mL per six hours or greater) vs lower threshold (less than 500 mL per six hours) at time of aspiration

Mortality (at the end of · adults receiving EN via nasogastric or gastrostomy tube

It is very uncertain whether higher threshold (500 mL per six hours or greater) changes mortality (at the end of compared with lower threshold (less than 500 mL per six hours) at time of aspiration (very low certainty).

1 finding from 1 review

Higher threshold (500 mL per six hours or greater) vs lower threshold (less than 500 mL per six hours) at time of aspiration

Pneumonia · adults receiving EN via nasogastric or gastrostomy tube

It is very uncertain whether higher threshold (500 mL per six hours or greater) changes pneumonia (until discontinued or up to 28 days) compared with lower threshold (less than 500 mL per six hours) at time of aspiration (very low certainty).

1 finding from 1 review

Minimally invasive parathyroidectomy vs bilateral neck exploration

Success rate (eucalcaemia) (a)

It is very uncertain whether minimally invasive parathyroidectomy changes success rate (eucalcaemia) (a) compared with bilateral neck exploration (very low certainty).

1 finding from 1 review

Minimally invasive parathyroidectomy vs bilateral neck exploration

Adverse effects: perioperative complications (number of events)

Minimally invasive parathyroidectomy may leads to lower total incidence of perioperative adverse events (number) compared with bilateral neck exploration (low certainty).

1 finding from 1 review