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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

775 questions in 58 reviews · Bone, Joint and Muscle Trauma

current versions
No studies 166 · 21.4%Ungraded 24 · 3.1%Very low 356 · 45.9%Low 162 · 20.9%Moderate 47 · 6.1%High 20 · 2.6%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Assistive technology for vision improvement interventions vs usual care or attention control
Number of people who experienced 1 or more hospitalisations following a fall · older people living in the community
Environmental interventions for preventing falls in older people living in the community (2023) · Cochrane
no estimate extractedNRNo studies
Assistive technology for vision improvement interventions vs usual care or attention control
Rate of falls requiring medical attention · older people living in the community
Environmental interventions for preventing falls in older people living in the community (2023) · Cochrane
0.93 [0.48, 1.82]1 study · 276 participantsVery low
Assistive technology for vision improvement interventions vs usual care or attention control
Health‐related quality of life 1 trial of single‐lens glasses compared with usual glasses (multifocals) reported this outcome using the SF‐12 (range 0 to 100). Higher scores indicate better quality of life. · older people living in the community
Environmental interventions for preventing falls in older people living in the community (2023) · Cochrane
MD 0.41 study · 597 participantsLow
Assistive technology for vision improvement interventions vs usual care or attention control
Adverse events Falls while switching glasses · older people living in the community
Environmental interventions for preventing falls in older people living in the community (2023) · Cochrane
RR 1 [0.98, 1.02]1 study · 597 participantsLow
Education interventions vs control (e.g. usual care)
Rate of falls (falls per person‐years) · older people living in the community
Environmental interventions for preventing falls in older people living in the community (2023) · Cochrane
Rate ratio 0.63 [0.37, 1.07]1 study · 110 participantsVery low
Education interventions vs control (e.g. usual care)
Number of people who experienced 1 or more falls · older people living in the community
Environmental interventions for preventing falls in older people living in the community (2023) · Cochrane
RR 0.84 [0.64, 1.11]1 study · 110 participantsVery low
Education interventions vs control (e.g. usual care)
Number of people who experienced 1 or more fall‐related fractures · older people living in the community
Environmental interventions for preventing falls in older people living in the community (2023) · Cochrane
RR 1.02 [0.96, 1.08]1 study · 110 participantsLow
Education interventions vs control (e.g. usual care)
Number of people who experienced 1 or more falls requiring hospitalisation · older people living in the community
Environmental interventions for preventing falls in older people living in the community (2023) · Cochrane
no estimate extractedNRNo studies
Education interventions vs control (e.g. usual care)
Number of people who experienced 1 or more falls requiring medical attention · older people living in the community
Environmental interventions for preventing falls in older people living in the community (2023) · Cochrane
no estimate extractedNRNo studies
Home fall‐hazard reduction vs control (e.g. usual care)
Number of people who experienced 1 or more falls · older people living in the community (included trials conducting pre‐ and/or post‐hospital discharge home visits…
Environmental interventions for preventing falls in older people living in the community (2023) · Cochrane
RR 0.89 [0.82, 0.97]12 studies · 5253 participantsModerate
Education interventions vs control (e.g. usual care)
Health‐related quality of life · older people living in the community
Environmental interventions for preventing falls in older people living in the community (2023) · Cochrane
no estimate extractedNRNo studies
Education interventions vs control (e.g. usual care)
Adverse events · older people living in the community
Environmental interventions for preventing falls in older people living in the community (2023) · Cochrane
no estimate extractedNRNo studies
Home fall‐hazard reduction vs control (e.g. usual care)
Number of people who experienced 1 or more fall‐related fractures · older people living in the community (included trials conducting pre‐ and/or post‐hospital discharge home visits…
Environmental interventions for preventing falls in older people living in the community (2023) · Cochrane
RR 1 [0.98, 1.02]2 studies · 1668 participantsVery low
Home fall‐hazard reduction vs control (e.g. usual care)
Number of people who experienced 1 or more falls that resulted in hospital admission · older people living in the community (included trials conducting pre‐ and/or post‐hospital discharge home visits…
Environmental interventions for preventing falls in older people living in the community (2023) · Cochrane
RR 0.96 [0.87, 1.06]3 studies · 325 participantsLow
Home fall‐hazard reduction vs control (e.g. usual care)
Falls requiring medical attention Rate of falls requiring medical attention · older people living in the community (included trials conducting pre‐ and/or post‐hospital discharge home visits…
Environmental interventions for preventing falls in older people living in the community (2023) · Cochrane
0.91 [0.58, 1.43]3 studies · 946 participantsLow
Home fall‐hazard reduction vs control (e.g. usual care)
Health‐related quality of life SMD was calculated from 4 studies with EQ‐5D (range 0 to 1), 1 study with SF‐36, and 1 study with WHOQOL‐BREF (range 0 to 100). Higher scores indicate better quality of life. · older people living in the community (included trials conducting pre‐ and/or post‐hospital discharge home visits…
Environmental interventions for preventing falls in older people living in the community (2023) · Cochrane
SMD 0.096 studies · 1848 participantsModerate
Home fall‐hazard reduction vs control (e.g. usual care)
Adverse events · older people living in the community (included trials conducting pre‐ and/or post‐hospital discharge home visits…
Environmental interventions for preventing falls in older people living in the community (2023) · Cochrane
no estimate extracted2 studies · 73 participantsLow
Assistive technology for vision improvement interventions vs usual care or attention control
Rate of falls (falls per person‐years) · older people living in the community
Environmental interventions for preventing falls in older people living in the community (2023) · Cochrane
Rate ratio 1.12 [0.84, 1.5]3 studies · 1489 participantsLow
Assistive technology for vision improvement interventions vs usual care or attention control
Number of people who experienced 1 or more falls · older people living in the community
Environmental interventions for preventing falls in older people living in the community (2023) · Cochrane
RR 1.09 [0.79, 1.5]3 studies · 1489 participantsLow
CBT interventions (CBT with and without exercise) vs control (standard care or sham treatments)
FoF (immediate postintervention)a · older adults (mean age minus 1 standard deviation is more than 60 years)
Cognitive behavioural therapy (CBT) with and without exercise to reduce fear of falling in older people… (2023) · Cochrane
no estimate extracted11 studies · 2357 participantsModerate
CBT interventions (CBT with and without exercise) vs control (standard care or sham treatments)
FoF (sustainability of effects, up to 6 months' postintervention) · older adults (mean age minus 1 standard deviation is more than 60 years)
Cognitive behavioural therapy (CBT) with and without exercise to reduce fear of falling in older people… (2023) · Cochrane
no estimate extracted8 studies · 1784 participantsLow
CBT interventions (CBT with and without exercise) vs control (standard care or sham treatments)
FoF (sustainability of effects, > 6 months' postintervention) · older adults (mean age minus 1 standard deviation is more than 60 years)
Cognitive behavioural therapy (CBT) with and without exercise to reduce fear of falling in older people… (2023) · Cochrane
no estimate extracted5 studies · 1185 participantsModerate
CBT interventions (CBT with and without exercise) vs control (standard care or sham treatments)
Activity avoidance · older adults (mean age minus 1 standard deviation is more than 60 years)
Cognitive behavioural therapy (CBT) with and without exercise to reduce fear of falling in older people… (2023) · Cochrane
no estimate extracted1 study · 312 participantsLow
CBT interventions (CBT with and without exercise) vs control (standard care or sham treatments)
Occurrence of falls · older adults (mean age minus 1 standard deviation is more than 60 years)
Cognitive behavioural therapy (CBT) with and without exercise to reduce fear of falling in older people… (2023) · Cochrane
RR 0.96 [0.66, 1.39]5 studies · 1119 participantsVery low
CBT interventions (CBT with and without exercise) vs control (standard care or sham treatments)
Depression · older adults (mean age minus 1 standard deviation is more than 60 years)
Cognitive behavioural therapy (CBT) with and without exercise to reduce fear of falling in older people… (2023) · Cochrane
no estimate extracted1 study · 314 participantsLow
CBT interventions (CBT with and without exercise) vs control (standard care or sham treatments)
Adverse effects · older adults (mean age minus 1 standard deviation is more than 60 years)
Cognitive behavioural therapy (CBT) with and without exercise to reduce fear of falling in older people… (2023) · Cochrane
no estimate extractedNRNo studies
Cephalomedullary nails vs extramedullary implants
Activities of daily living (ADL), early (≤ 4 months): using LEM (range from 0 to 100), FIM (range from 0 to 100), JOA (range from 0 to 20); higher scores indicate better performance in ADL · older adults with stable or unstable extracapsular hip fractures
Cephalomedullary nails versus extramedullary implants for extracapsular hip fractures in older adults (2022) · Cochrane
no estimate extracted4 studies · 509 participantsVery low
Cephalomedullary nails vs extramedullary implants
Delirium (at end of · older adults with stable or unstable extracapsular hip fractures
Cephalomedullary nails versus extramedullary implants for extracapsular hip fractures in older adults (2022) · Cochrane
RR 1.22 [0.67, 2.22]5 studies · 1310 participantsLow
Cephalomedullary nails vs extramedullary implants
Functional status, early (≤ 4 months): using Zűckerman functional recovery score (0 to 44), and 100‐point functional recovery scale; in both scales, higher scores indicate better function · older adults with stable or unstable extracapsular hip fractures
Cephalomedullary nails versus extramedullary implants for extracapsular hip fractures in older adults (2022) · Cochrane
SMD 0.022 studies · 188 participantsLow
Cephalomedullary nails vs extramedullary implants
Health‐related quality of life, early (≤ 4 months) · older adults with stable or unstable extracapsular hip fractures
Cephalomedullary nails versus extramedullary implants for extracapsular hip fractures in older adults (2022) · Cochrane
no estimate extractedNRNo studies
Cephalomedullary nails vs extramedullary implants
Mobility (≤ 4 months): assessed as number of participants with independent mobility · older adults with stable or unstable extracapsular hip fractures
Cephalomedullary nails versus extramedullary implants for extracapsular hip fractures in older adults (2022) · Cochrane
RR 1.12 [1.01, 1.23]7 studies · 719 participantsVery low
Cephalomedullary nails vs extramedullary implants
Mortality, early (≤ 4 months) · older adults with stable or unstable extracapsular hip fractures
Cephalomedullary nails versus extramedullary implants for extracapsular hip fractures in older adults (2022) · Cochrane
RR 0.96 [0.79, 1.18]30 studies · 4603 participantsModerate
Cephalomedullary nails vs extramedullary implants
Mortality at 12 months · older adults with stable or unstable extracapsular hip fractures
Cephalomedullary nails versus extramedullary implants for extracapsular hip fractures in older adults (2022) · Cochrane
RR 0.99 [0.9, 1.08]47 studies · 7618 participantsModerate
Cephalomedullary nails vs extramedullary implants
Unplanned return to theatre (at end of · older adults with stable or unstable extracapsular hip fractures
Cephalomedullary nails versus extramedullary implants for extracapsular hip fractures in older adults (2022) · Cochrane
RR 1.15 [0.89, 1.5]50 studies · 8398 participantsLow
Early vs delayed mobilisation
Self‐reported shoulder function: Croft Shoulder Disability Score (1 or more problems) · adults with minimally displaced or displaced (2‐part or 3‐part) proximal humeral fractures treated non‐surgically (5…
Interventions for treating proximal humeral fractures in adults (2022) · Cochrane
RR 0.59 [0.4, 0.88]1 study · 82 participantsVery low
Surgical vs non‐surgical treatment
Functional scoresf(higher = better outcome) · (mainly older) adults with most types of displaced proximal humeral fracturesa (10 trials)
Interventions for treating proximal humeral fractures in adults (2022) · Cochrane
SMD 0.065 studies · 423 participantsHigh
Surgical vs non‐surgical treatment
Quality of life: EQ‐5D (0: dead to 1: best quality of life) · (mainly older) adults with most types of displaced proximal humeral fracturesa (10 trials)
Interventions for treating proximal humeral fractures in adults (2022) · Cochrane
MD 0.016 studies · 502 participantsHigh
Surgical vs non‐surgical treatment
Mortality · (mainly older) adults with most types of displaced proximal humeral fracturesa (10 trials)
Interventions for treating proximal humeral fractures in adults (2022) · Cochrane
RR 1.35 [0.7, 2.62]8 studies · 646 participantsLow
Surgical vs non‐surgical treatment
Additional surgery (reoperation or secondary surgery) · (mainly older) adults with most types of displaced proximal humeral fracturesa (10 trials)
Interventions for treating proximal humeral fractures in adults (2022) · Cochrane
RR 2.06 [1.21, 3.51]9 studies · 667 participantsLow
Surgical vs non‐surgical treatment
Adverse events / complications ‐ Number of participants with complications · (mainly older) adults with most types of displaced proximal humeral fracturesa (10 trials)
Interventions for treating proximal humeral fractures in adults (2022) · Cochrane
RR 1.46 [0.92, 2.31]3 studies · 391 participantsLow
Locking plate vs locking intramedullary nail
Self‐reported shoulder function: functional scoresb(higher = better outcome) · adults undergoing surgery for displaced proximal humeral fracturesa (4 trials)
Interventions for treating proximal humeral fractures in adults (2022) · Cochrane
SMD 0.154 studies · 227 participantsLow
Locking plate vs locking intramedullary nail
Self‐reported shoulder function: DASH (0 to 100: higher = worse disability)b · adults undergoing surgery for displaced proximal humeral fracturesa (4 trials)
Interventions for treating proximal humeral fractures in adults (2022) · Cochrane
no estimate extracted3 studies · 174 participantsLow
Locking plate vs locking intramedullary nail
Self‐reported shoulder function: ASES (0 to 100: best outcome)b · adults undergoing surgery for displaced proximal humeral fracturesa (4 trials)
Interventions for treating proximal humeral fractures in adults (2022) · Cochrane
no estimate extracted2 studies · 101 participantsLow
Locking plate vs locking intramedullary nail
Quality of life: SF‐36 (0 to 100: best outcome) · adults undergoing surgery for displaced proximal humeral fracturesa (4 trials)
Interventions for treating proximal humeral fractures in adults (2022) · Cochrane
no estimate extracted1 study · 53 participantsVery low
Locking plate vs locking intramedullary nail
Mortality · adults undergoing surgery for displaced proximal humeral fracturesa (4 trials)
Interventions for treating proximal humeral fractures in adults (2022) · Cochrane
no estimate extracted3 studies · 176 participantsVery low
Early vs delayed mobilisation
Self‐reported shoulder function: DASH(0 to 100: worst outcome) · adults with minimally displaced or displaced (2‐part or 3‐part) proximal humeral fractures treated non‐surgically (5…
Interventions for treating proximal humeral fractures in adults (2022) · Cochrane
no estimate extracted1 study · 50 participantsVery low
Locking plate vs locking intramedullary nail
Adverse events: number of participants with complications · adults undergoing surgery for displaced proximal humeral fracturesa (4 trials)
Interventions for treating proximal humeral fractures in adults (2022) · Cochrane
RR 1.11 [0.7, 1.75]4 studies · 250 participantsVery low
Locking plate vs locking intramedullary nail
Additional surgery (reoperation or secondary surgery) · adults undergoing surgery for displaced proximal humeral fracturesa (4 trials)
Interventions for treating proximal humeral fractures in adults (2022) · Cochrane
RR 0.73 [0.33, 1.61]3 studies · 193 participantsVery low
Reverse total shoulder arthroplasty (RTSA) vs hemiarthroplasty
Self‐reported shoulder function: % of normal shoulder function based on WOOS score (higher = better outcome) · adults undergoing surgery for displaced proximal humeral fracturesa (2 trials)
Interventions for treating proximal humeral fractures in adults (2022) · Cochrane
no estimate extracted1 study · 65 participantsVery low
Reverse total shoulder arthroplasty (RTSA) vs hemiarthroplasty
Self‐reported shoulder function · adults undergoing surgery for displaced proximal humeral fracturesa (2 trials)
Interventions for treating proximal humeral fractures in adults (2022) · Cochrane
no estimate extractedNRNo studies