Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

47 questions · 48 findings · 7 reviews · Vascular

No studies found 15 · 31.3%GRADE not reported 0 · 0%Very low 4 · 8.3%Low 19 · 39.6%Moderate 10 · 20.8%High 0 · 0%

Low molecular weight heparin vs unfractionated heparin

Success rate of replantation1 (analysed by participant) · patients undergoing digital replantation after traumatic amputation

It is very uncertain whether low molecular weight heparin changes success rate of replantation1 (analysed by participant, compared with unfractionated heparin (very low certainty).

1 finding from 1 review

Low molecular weight heparin vs unfractionated heparin

Success rate of replantation1 (analysed by digit, · patients undergoing digital replantation after traumatic amputation

Low molecular weight heparin showed no clear difference in success rate of replantation1 (analysed by digit, compared with unfractionated heparin (low certainty).

1 finding from 1 review

Low molecular weight heparin vs unfractionated heparin

Incidence of compromised microcirculation requiring invasive intervention (re‐exploration) (analysed by digit, · patients undergoing digital replantation after traumatic amputation

The review found no eligible studies for this question.

1 finding from 1 review

Low molecular weight heparin vs unfractionated heparin

Incidence of compromised microcirculation requiring invasive intervention (incision) (analysed by participant/digit, · patients undergoing digital replantation after traumatic amputation

The review found no eligible studies for this question.

1 finding from 1 review

Low molecular weight heparin vs unfractionated heparin

Microvascular insufficiency due to vessel occlusion ‐ arterial occlusion (analysed by digit, · patients undergoing digital replantation after traumatic amputation

It is very uncertain whether low molecular weight heparin changes microvascular insufficiency due to vessel occlusion ‐ arterial… compared with unfractionated heparin (very low certainty).

1 finding from 1 review

Low molecular weight heparin vs unfractionated heparin

Microvascular insufficiency due to vessel occlusion ‐ venous occlusion (analysed by participant, · patients undergoing digital replantation after traumatic amputation

It is very uncertain whether low molecular weight heparin changes microvascular insufficiency due to vessel occlusion ‐ venous… compared with unfractionated heparin (very low certainty).

1 finding from 1 review

Low molecular weight heparin vs unfractionated heparin

Complication and adverse reactions ‐ wound bleeding (analysed by participant, · patients undergoing digital replantation after traumatic amputation

Low molecular weight heparin showed no clear difference in complication and adverse reactions ‐ wound bleeding (analysed by… compared with unfractionated heparin (low certainty).

1 finding from 1 review

Intervention not reported

Heparin‐induced thrombocytopenia (HIT) · people undergoing surgical procedures and treated with UFH or LMWH for prophylaxis of thrombotic events lasting at least 5 days

The intervention may leads to lower heparin‐induced thrombocytopenia (HIT) (low certainty).

1 finding from 1 review

Intervention not reported

Other thrombotic events: venous thrombosis (up to 48 hours after CC) · children with congenital heart disease undergoing CC

The intervention showed no clear difference in other thrombotic events: venous thrombosis (up to 48 hours after CC) (moderate certainty).

1 finding from 1 review