Findings

What do systematic reviews say?

25 questions · 25 findings · 2 reviews

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No studies found 7 · 28%GRADE not reported 1 · 4%Very low 1 · 4%Low 5 · 20%Moderate 6 · 24%High 5 · 20%

Azelaic acid vs topical metronidazole

Assessment of erythema or telangiectasia · Participants with rosacea

1 finding from 1 review

Interventions for rosacea 2015 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 491 participants
Low

Azelaic acid vs topical metronidazole

Lesion count · Participants with rosacea

1 finding from 1 review

Interventions for rosacea 2015 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 491 participants
Moderate

Azelaic acid vs topical metronidazole

Time needed until improvement of the skin lesions · Participants with rosacea

1 finding from 1 review

Interventions for rosacea 2015 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 491 participants
GRADE not reported

Azelaic acid vs topical metronidazole

Duration of remission ‐ not measured · Participants with rosacea

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for rosacea 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antibiotics vs no treatment or placebo on top of topical antibiotics

Resolution of ear discharge ‐ measured after 4 weeks · people with CSOM; one study included patients of unknown age; one study included children with CSOM who had not responded to initial…

It is very uncertain whether systemic antibiotics changes resolution of ear discharge ‐ measured after 4 weeks (4 weeks)… compared with no treatment or placebo on top of topical antibiotics (very low certainty).

1 finding from 1 review

Systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
RR 0.91 [0.51, 1.65]
1 study · 30 participants
Very low