Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

25 questions · 25 findings · 2 reviews

No studies found 7 · 28%GRADE not reported 1 · 4%Very low 1 · 4%Low 5 · 20%Moderate 6 · 24%High 5 · 20%

Topical ivermectin vs topical metronidazole

QoL · Participants with rosacea

Topical ivermectin leads to higher HRQOL DLQI, proportion of participants that reported at end of study… compared with topical metronidazole (high certainty).

1 finding from 1 review

Topical ivermectin vs topical metronidazole

Participant‐assessed improvement in rosacea severity · Participants with rosacea

Topical ivermectin leads to higher participant‐assessed improvement in rosacea severity Likert scale ‐… compared with topical metronidazole (high certainty).

1 finding from 1 review

Topical ivermectin vs topical metronidazole

Proportion of participants with adverse event · Participants with rosacea

Topical ivermectin showed no clear difference in proportion of participants with adverse event compared with topical metronidazole (moderate certainty).

1 finding from 1 review

Topical ivermectin vs topical metronidazole

Physician‐assessed improvement in rosacea severity · Participants with rosacea

Topical ivermectin leads to higher physician‐assessed improvement in rosacea severity compared with topical metronidazole (high certainty).

1 finding from 1 review