What do systematic reviews say?

Topical antimicrobial agent vs growth factor

The review found no eligible studies for this question.

• Topical antimicrobial agents for treating foot ulcers in people with diabetes 2017 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Topical antimicrobial agent vs alternative antimicrobial agent

• Topical treatment for facial burns 2020 · Cochrane Headline outcomes only
  no estimate extracted
  142 participants
  Low

Topical antimicrobial agent vs alternative antimicrobial agent

It is very uncertain whether topical antimicrobial changes infection (until wound healing) compared with alternative antimicrobial agent (very low certainty).

• Topical treatment for facial burns 2020 · Cochrane Headline outcomes only
  RR 0.73 [0.46, 1.17]
  15 participants
  Very low

Topical antimicrobial agent vs alternative antimicrobial agent

The review found no eligible studies for this question.

• Topical treatment for facial burns 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Topical antimicrobial agent vs alternative antimicrobial agent

The review found no eligible studies for this question.

• Topical treatment for facial burns 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Topical antimicrobial agent vs alternative antimicrobial agent

The review found no eligible studies for this question.

• Topical treatment for facial burns 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Antimicrobial dressings vs non‐antimicrobial dressings

Antimicrobial dressings may leads to higher proportion of wounds healed Up to 24 weeks' compared with non‐antimicrobial dressings (low certainty).

• Topical antimicrobial agents for treating foot ulcers in people with diabetes 2017 · Cochrane Headline outcomes only
  RR 1.28 [1.12, 1.45]
  5 studies · 945 participants
  Low

Antimicrobial dressings vs non‐antimicrobial dressings

It is very uncertain whether antimicrobial dressings changes incidence of infection Up to 24 weeks' compared with non‐antimicrobial dressings (very low certainty).

• Topical antimicrobial agents for treating foot ulcers in people with diabetes 2017 · Cochrane Headline outcomes only
  RR 0.34 [0.04, 3.1]
  2 studies · 173 participants
  Very low

Antimicrobial dressings vs non‐antimicrobial dressings

The review found no eligible studies for this question.

• Topical antimicrobial agents for treating foot ulcers in people with diabetes 2017 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Antimicrobial dressings vs non‐antimicrobial dressings

It is very uncertain whether antimicrobial dressings changes adverse events Up to 24 weeks' compared with non‐antimicrobial dressings (very low certainty).

• Topical antimicrobial agents for treating foot ulcers in people with diabetes 2017 · Cochrane Headline outcomes only
  RR 0.96 [0.62, 1.48]
  1 study · 134 participants
  Very low

Topical disinfectants vs standard care or other active treatment (antibiotic or other disinfectant)

Topical disinfectants showed no clear difference in peritonitis (number of patients with one or more episodes) compared with standard care or other active treatment (antibiotic or other… (low certainty).

• Antimicrobial agents for preventing peritonitis in peritoneal dialysis patients 2017 · Cochrane Headline outcomes only
  RR 0.83 [0.65, 1.06]
  6 studies · 853 participants
  Low

Topical disinfectants vs standard care or other active treatment (antibiotic or other disinfectant)

Topical disinfectants showed no clear difference in exit‐site/tunnel infection (number of patients with one or more… compared with standard care or other active treatment (antibiotic or other… (low certainty).

• Antimicrobial agents for preventing peritonitis in peritoneal dialysis patients 2017 · Cochrane Headline outcomes only
  RR 0.97 [0.74, 1.27]
  7 studies · 913 participants
  Low

Topical disinfectants vs standard care or other active treatment (antibiotic or other disinfectant)

Topical disinfectants showed no clear difference in catheter removal or replacement (number of patients) compared with standard care or other active treatment (antibiotic or other… (low certainty).

• Antimicrobial agents for preventing peritonitis in peritoneal dialysis patients 2017 · Cochrane Headline outcomes only
  RR 0.89 [0.57, 1.38]
  6 studies · 792 participants
  Low

Oral or topical or intraperitoneal antibiotics vs placebo/no treatment

Oral or topical or intraperitoneal antibiotics showed no clear difference in peritonitis (number of patients with one or more episodes) compared with placebo/no treatment (low certainty).

• Antimicrobial agents for preventing peritonitis in peritoneal dialysis patients 2017 · Cochrane Headline outcomes only
  RR 0.82 [0.57, 1.19]
  5 studies · 395 participants
  Low

Oral or topical or intraperitoneal antibiotics vs placebo/no treatment

Oral or topical or intraperitoneal antibiotics showed no clear difference in exit‐site/tunnel infection (number of patients with one or more… compared with placebo/no treatment (low certainty).

• Antimicrobial agents for preventing peritonitis in peritoneal dialysis patients 2017 · Cochrane Headline outcomes only
  RR 0.45 [0.19, 1.04]
  3 studies · 191 participants
  Low

Oral or topical or intraperitoneal antibiotics vs placebo/no treatment

Oral or topical or intraperitoneal antibiotics showed no clear difference in catheter removal or replacement (number of patients) compared with placebo/no treatment (low certainty).

• Antimicrobial agents for preventing peritonitis in peritoneal dialysis patients 2017 · Cochrane Headline outcomes only
  RR 0.82 [0.46, 1.46]
  5 studies · 395 participants
  Low

Skin substitute vs topical antimicrobial agent

The review found no eligible studies for this question.

• Topical treatment for facial burns 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Skin substitute vs topical antimicrobial agent

The review found no eligible studies for this question.

• Topical treatment for facial burns 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Skin substitute vs topical antimicrobial agent

The review found no eligible studies for this question.

• Topical treatment for facial burns 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Skin substitute vs topical antimicrobial agent

• Topical treatment for facial burns 2020 · Cochrane Headline outcomes only
  no estimate extracted
  34 participants
  Low