Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

216 questions · 222 findings · 3 reviews · Endodontics and dental trauma

No studies found 8 · 3.6%GRADE not reported 150 · 67.6%Very low 29 · 13.1%Low 26 · 11.7%Moderate 9 · 4.1%High 0 · 0%

Biodentine vs Tempophore

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Biodentine showed no clear difference in radiological failure compared with tempophore; GRADE not reported.

1 finding from 1 review

Zinc oxide and eugenol (ZOE) vs Zinc oxide and propolis (ZOP)

Outcome not reported · Children with extensive decay involving the dental pulp in primary teeth

The review found no eligible studies for this question.

1 finding from 1 review

Self-etch adhesive + acetone-based total-etch adhesive vs Acetone-based total-etch adhesive

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

It is very uncertain whether self-etch adhesive + acetone-based total-etch adhesive changes clinical failure compared with acetone-based total-etch adhesive (very low certainty).

1 finding from 1 review

Enamel matrix derivative (EMD) vs Calcium hydroxide (CH)

Outcome not reported · Children with extensive decay involving the dental pulp in primary teeth
1 finding from 1 review
  • Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
    6 and 12 months
    Direct pulp capping; overall failure RR 1.00 (0.06 to 15.50) at 6/12 months (Garrocho-Rangel 2009); no pain/soft tissue/mobility/root resorption
    1 study · 90 participants
    GRADE not reported

3Mix (ciprofloxacin + metronidazole + minocycline) vs Ciprofloxacin + ornidazole + minocycline

Outcome not reported · Children with extensive decay involving the dental pulp in primary teeth

The review found no eligible studies for this question.

1 finding from 1 review

Glutaraldehyde + calcium hydroxide (CH) vs Full strength formocresol (FC)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Glutaraldehyde + calcium hydroxide (CH) showed no clear difference in radiological failure compared with full strength formocresol (FC); GRADE not reported.

1 finding from 1 review

Mineral trioxide aggregate (MTA) + sodium hypochlorite (NaOCl) vs Calcium hydroxide + sodium hypochlorite (NaOCl)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Mineral trioxide aggregate (MTA) + sodium hypochlorite (NaOCl) showed no clear difference in radiological failure compared with calcium hydroxide + sodium hypochlorite (NaOCl); GRADE not reported.

1 finding from 1 review

Sealapex (eugenol-free calcium hydroxide) vs Zinc oxide and eugenol (ZOE)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Sealapex (eugenol-free calcium hydroxide) showed no clear difference in radiological failure compared with zinc oxide and eugenol (ZOE); GRADE not reported.

1 finding from 1 review