Question · asked by 1 review

Enamel matrix derivative (EMD; Emdogain) vs Formocresol (FC): Radiological failure

Population
Children with extensive decay involving the dental pulp in primary teeth
Intervention
Enamel matrix derivative (EMD; Emdogain)
Comparison
Formocresol (FC)
Outcome
Radiological failure

Enamel matrix derivative (EMD) led to lower radiological failure compared with formocresol (FC); GRADE not reported.

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Enamel matrix derivative (EMD) vs Formocresol (FC)
Radiological failure · Children with extensive decay involving the dental pulp in primary teeth · 6 months
Enamel matrix derivative (EMD) led to lower radiological failure compared with formocresol (FC); GRADE not reported.
Pulp treatment for extensive decay in primary teeth (2018) · Cochrane All outcomes
RR 0.46 [0.24, 0.88]1 study · 30 participantsGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Pulp treatment for extensive decay in primary teeth
2018 · Cochrane All outcomes
2017-08Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.