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Evidence found and GRADE certainty

158 questions · 174 findings · 22 reviews · Gut

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No studies found 20 · 11.5%GRADE not reported 7 · 4%Very low 79 · 45.4%Low 31 · 17.8%Moderate 25 · 14.4%High 12 · 6.9%

Proton pump inhibitors (PPI) vs H2RA, placebo or no treatment

Surgery ‐ within 30 days · people with upper gastrointestinal bleeding prior to endoscopic diagnosis

Proton pump inhibitor treatment showed no clear difference in surgery ‐ within 30 days compared with H2RA, placebo or no treatment (low certainty).

1 finding from 1 review

Intervention not reported

Quality of life (EQ‐5D, EORTC QLQ‐C30 and PAN26, GIQLI at 2, 4 and 12 weeks after surgery) · adults with any pancreatic diagnosis leading to an indication for elective (classical, pylorus‐preserving, pylorus‐resecting) partial…
1 finding from 1 review

Corticosteroids vs control

Infectious complications · people with inflammatory bowel disease

It is very uncertain whether risk of postoperative infectious complications: corticosteroids changes overall infectious complications within 30 days of surgery compared with control (very low certainty).

3 findings from 1 review

5‐ASA vs control

Incisional infections and wound dehiscence within 30 days of surgery · people with inflammatory bowel disease

Risk of postoperative infectious complications: 5‐ASA led to lower incisional infections and wound dehiscence within 30 days of surgery compared with control; GRADE not reported.

1 finding from 1 review

5‐ASA vs control

Intra‐abdominal infectious complications within 30 days of surgery · people with inflammatory bowel disease

It is very uncertain whether risk of postoperative infectious complications: 5‐ASA changes intra‐abdominal infectious complications within 30 days of surgery compared with control (very low certainty).

1 finding from 1 review

Risk of postoperative infectious complications: immunomodulators vs control

Infectious complications · people with inflammatory bowel disease

It is very uncertain whether risk of postoperative infectious complications: immunomodulators changes overall infectious complications within 30 days of surgery compared with control (very low certainty).

3 findings from 1 review

Risk of postoperative infectious complications: immunomodulators vs control

Incisional infections and wound dehiscence within 30 days of surgery · people with inflammatory bowel disease

It is very uncertain whether risk of postoperative infectious complications: immunomodulators changes incisional infections and wound dehiscence within 30 days of surgery compared with control (very low certainty).

1 finding from 1 review

Risk of postoperative infectious complications: immunomodulators vs control

Intra‐abdominal infectious complications within 30 days of surgery · people with inflammatory bowel disease

It is very uncertain whether risk of postoperative infectious complications: immunomodulators changes intra‐abdominal infectious complications within 30 days of surgery compared with control (very low certainty).

1 finding from 1 review

Risk of postoperative infectious complications: immunomodulators vs control

Extra‐abdominal infections within 30 days of surgery · people with inflammatory bowel disease

It is very uncertain whether risk of postoperative infectious complications: immunomodulators changes extra‐abdominal infections within 30 days of surgery compared with control (very low certainty).

1 finding from 1 review

Risk of postoperative infectious complications: anti‐TNF agents vs control

Infectious complications · people with inflammatory bowel disease

It is very uncertain whether risk of postoperative infectious complications: anti‐TNF agents changes overall infectious complications within 30 days of surgery compared with control (very low certainty).

3 findings from 1 review

Risk of postoperative infectious complications: anti‐TNF agents vs control

Incisional infections and wound dehiscence within 30 days of surgery · people with inflammatory bowel disease

It is very uncertain whether risk of postoperative infectious complications: anti‐TNF agents changes incisional infections and wound dehiscence within 30 days of surgery compared with control (very low certainty).

1 finding from 1 review

Risk of postoperative infectious complications: anti‐TNF agents vs control

Intra‐abdominal infectious complications within 30 days of surgery · people with inflammatory bowel disease

It is very uncertain whether risk of postoperative infectious complications: anti‐TNF agents changes intra‐abdominal infectious complications within 30 days of surgery compared with control (very low certainty).

1 finding from 1 review

Risk of postoperative infectious complications: anti‐TNF agents vs control

Extra‐abdominal infections within 30 days of surgery · people with inflammatory bowel disease

It is very uncertain whether risk of postoperative infectious complications: anti‐TNF agents changes extra‐abdominal infections within 30 days of surgery compared with control (very low certainty).

1 finding from 1 review

Risk of postoperative infectious complications: anti‐integrin agents vs control

Infectious complications · people with inflammatory bowel disease

It is very uncertain whether risk of postoperative infectious complications: anti‐integrin agents changes overall infectious complications within 30 days of surgery compared with control (very low certainty).

3 findings from 1 review

Risk of postoperative infectious complications: anti‐integrin agents vs control

Incisional infections and wound dehiscence within 30 days of surgery · people with inflammatory bowel disease

It is very uncertain whether risk of postoperative infectious complications: anti‐integrin agents changes incisional infections and wound dehiscence within 30 days of surgery compared with control (very low certainty).

1 finding from 1 review

Risk of postoperative infectious complications: anti‐integrin agents vs control

Intra‐abdominal infectious complications within 30 days of surgery · people with inflammatory bowel disease

It is very uncertain whether risk of postoperative infectious complications: anti‐integrin agents changes intra‐abdominal infectious complications within 30 days of surgery compared with control (very low certainty).

1 finding from 1 review

Risk of postoperative infectious complications: anti‐integrin agents vs control

Extra‐abdominal infections within 30 days of surgery · people with inflammatory bowel disease

It is very uncertain whether risk of postoperative infectious complications: anti‐integrin agents changes extra‐abdominal infections within 30 days of surgery compared with control (very low certainty).

1 finding from 1 review