Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

199 questions · 201 findings · 12 reviews · Pregnancy and Childbirth

No studies found 55 · 27.4%GRADE not reported 8 · 4%Very low 29 · 14.4%Low 57 · 28.4%Moderate 47 · 23.4%High 5 · 2.5%

Summary of findings table ‐ Remifentanil vs diazepam

Surgical assessment/satisfaction score = 1 or 2 (Technically successful procedure as defined by trial authors) · health problem or population

Summary of findings table ‐ Remifentanil may leads to higher surgical assessment/satisfaction score = 1 or 2 (Technically… compared with diazepam (low certainty).

1 finding from 1 review

Summary of findings table ‐ Remifentanil vs diazepam

Maternal OAA score (observer assessment of alertness/sedation) < 4 (Maternal sedation measured using sedation scores as defined by authors) · health problem or population

Summary of findings table ‐ Remifentanil may leads to lower maternal OAA score (observer assessment of alertness/sedation) < 4… compared with diazepam (low certainty).

1 finding from 1 review

Summary of findings for IV hexoprenaline vs no tocolytic agent, whilst awaiting emergency delivery

Perinatal death or severe morbidity · women for whom a decision had been made to deliver by caesarean section for suspected fetal distress based on FHR monitoring

The review found no eligible studies for this question.

1 finding from 1 review

Summary of findings for IV hexoprenaline vs no tocolytic agent, whilst awaiting emergency delivery

Fetal or neonatal mortality · women for whom a decision had been made to deliver by caesarean section for suspected fetal distress based on FHR monitoring

Summary of findings for IV hexoprenaline showed no clear difference in fetal or neonatal mortality compared with no tocolytic agent, whilst awaiting emergency delivery (low certainty).

1 finding from 1 review

Summary of findings for IV hexoprenaline vs no tocolytic agent, whilst awaiting emergency delivery

Apgar score less than 7 at 5 minutes · women for whom a decision had been made to deliver by caesarean section for suspected fetal distress based on FHR monitoring

Summary of findings for IV hexoprenaline showed no clear difference in 5‐minute Apgar score < 7 compared with no tocolytic agent, whilst awaiting emergency delivery (low certainty).

1 finding from 1 review

Summary of findings for IV hexoprenaline vs no tocolytic agent, whilst awaiting emergency delivery

Low umbilical artery pH (< 7.2 or as defined by trial authors) · women for whom a decision had been made to deliver by caesarean section for suspected fetal distress based on FHR monitoring

Summary of findings for IV hexoprenaline showed no clear difference in umbilical artery pH < 7.2 compared with no tocolytic agent, whilst awaiting emergency delivery (low certainty).

1 finding from 1 review

Summary of findings for IV hexoprenaline vs no tocolytic agent, whilst awaiting emergency delivery

Abnormal FHR as defined by trial authors (FHR tracing not improved) · women for whom a decision had been made to deliver by caesarean section for suspected fetal distress based on FHR monitoring

Summary of findings for IV hexoprenaline probably leads to lower FHR tracing not improved compared with no tocolytic agent, whilst awaiting emergency delivery (moderate certainty).

1 finding from 1 review

Summary of findings: Low‐moderate GI diet vs moderate‐high GI diet (maternal outcomes)

Hypertensive disorders of pregnancy: severe hypertension or pre‐eclampsia · pregnant women with GDM

It is very uncertain whether summary of findings: Low‐moderate GI diet changes hypertensive disorders of pregnancy: severe hypertension or… compared with moderate‐high GI diet (maternal outcomes) (very low certainty).

1 finding from 1 review