Findings

What do systematic reviews say?

30 questions · 32 findings · 4 reviews · Gynaecology and Fertility

No studies found 1 · 3.1%GRADE not reported 1 · 3.1%Very low 7 · 21.9%Low 9 · 28.1%Moderate 14 · 43.8%High 0 · 0%

Moderate dose SSRI versus placebo Luteal administration · women with premenstrual syndrome

1 finding from 1 review

Selective serotonin reuptake inhibitors for premenstrual syndrome 2013 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 457 participants
Moderate

Moderate dose SSRI versus placebo Continuous administration · women with premenstrual syndrome

1 finding from 1 review

Selective serotonin reuptake inhibitors for premenstrual syndrome 2013 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 843 participants
Low

Moderate dose SSRI versus placebo Luteal administration2 · women with premenstrual syndrome

1 finding from 1 review

Selective serotonin reuptake inhibitors for premenstrual syndrome 2013 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 657 participants
Moderate

Low dose SSRI versus placebo Luteal or continuous administration · women with premenstrual syndrome

The intervention probably leads to higher low dose SSRI versus placebo Luteal or continuous administration (moderate certainty).

1 finding from 1 review

Selective serotonin reuptake inhibitors for premenstrual syndrome 2013 · Cochrane Headline outcomes only
OR 1.76 [1.13, 2.75]
7 studies · 1301 participants
Moderate

Mod dose SSRI versus placebo Luteal or continuous administration · women with premenstrual syndrome

The intervention probably leads to higher mod dose SSRI versus placebo Luteal or continuous administration (moderate certainty).

1 finding from 1 review

Selective serotonin reuptake inhibitors for premenstrual syndrome 2013 · Cochrane Headline outcomes only
OR 2.55 [1.84, 3.53]
15 studies · 2447 participants
Moderate

High dose SSRIs versus placebo Continuous administration · women with premenstrual syndrome

The intervention probably leads to higher high dose SSRIs versus placebo Continuous administration (moderate certainty).

1 finding from 1 review

Selective serotonin reuptake inhibitors for premenstrual syndrome 2013 · Cochrane Headline outcomes only
RR 6.35 [2.88, 14]
1 study · 231 participants
Moderate

Percent change from baseline in leiomyoma size · patients with uterine leiomyomas

1 finding from 1 review

Selective estrogen receptor modulators (SERMs) for uterine leiomyomas 2012 · Cochrane Headline outcomes only
no estimate extracted
1 study · 23 participants
Very low

Size (cm3) of leiomyoma · patients with uterine leiomyomas

2 findings from 1 review

Selective estrogen receptor modulators (SERMs) for uterine leiomyomas 2012 · Cochrane Headline outcomes only
no estimate extracted
1 study · 58 participants
Low
Selective estrogen receptor modulators (SERMs) for uterine leiomyomas 2012 · Cochrane Headline outcomes only
no estimate extracted
1 study · 58 participants
Low

Percent change from baseline in leiomyoma size in GHRH‐analogue treated women · patients with uterine leiomyomas

1 finding from 1 review

Selective estrogen receptor modulators (SERMs) for uterine leiomyomas 2012 · Cochrane Headline outcomes only
no estimate extracted
1 study · 91 participants
Low

Size (cm3) of leiomyoma · patients with uterine leiomyomas

2 findings from 1 review

Selective estrogen receptor modulators (SERMs) for uterine leiomyomas 2012 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
Low
Selective estrogen receptor modulators (SERMs) for uterine leiomyomas 2012 · Cochrane Headline outcomes only
no estimate extracted
1 study · 59 participants
Low