Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

25 questions · 25 findings · 3 reviews · Pregnancy and Childbirth

No studies found 1 · 4%GRADE not reported 0 · 0%Very low 6 · 24%Low 4 · 16%Moderate 14 · 56%High 0 · 0%

Local and systemic reactions after administration of Tetanus Diphtheria acelluar Pertussis vaccine vs saline placebo

Systemic reactions ‐ headache · patients with local and systemic reactions

Local and systemic reactions after administration of Tetanus… showed no clear difference in systemic reactions ‐ headache compared with saline placebo (moderate certainty).

1 finding from 1 review

Local and systemic reactions after administration of Tetanus Diphtheria acelluar Pertussis vaccine vs saline placebo

Systemic reactions ‐ malaise · patients with local and systemic reactions

Local and systemic reactions after administration of Tetanus… showed no clear difference in systemic reactions ‐ malaise compared with saline placebo (moderate certainty).

1 finding from 1 review

Local and systemic reactions after administration of Tetanus Diphtheria acelluar Pertussis vaccine vs saline placebo

Systemic reactions ‐ myalgia · patients with local and systemic reactions

Local and systemic reactions after administration of Tetanus… showed no clear difference in systemic reactions ‐ myalgia compared with saline placebo (moderate certainty).

1 finding from 1 review

Local and systemic reactions after administration of Tetanus Diphtheria acelluar Pertussis vaccine vs saline placebo

Injection site pain · patients with local and systemic reactions

Local and systemic reactions after administration of Tetanus… probably leads to higher injection site reactions ‐ pain at injection site compared with saline placebo (moderate certainty).

1 finding from 1 review

Local and systemic reactions after administration of Tetanus Diphtheria acelluar Pertussis vaccine vs saline placebo

Injection site reactions ‐ erythema ‐ redness · patients with local and systemic reactions

Local and systemic reactions after administration of Tetanus… showed no clear difference in injection site reactions ‐ erythema ‐ redness compared with saline placebo (moderate certainty).

1 finding from 1 review