What do systematic reviews say?

Intervention not reported

The intervention probably leads to lower H2RA versus placebo (moderate certainty).

• Short‐term treatment with proton pump inhibitors, H2‐receptor antagonists and prokinetics for gastro‐oesophageal… 2013 · Cochrane Headline outcomes only
  RR 0.77 [0.6, 0.99]
  2 studies · 1013 participants
  Moderate

Intervention not reported

• Short‐term treatment with proton pump inhibitors, H2‐receptor antagonists and prokinetics for gastro‐oesophageal… 2013 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 322 participants
  High

Intervention not reported

The intervention probably leads to lower PPI versus H2RA (moderate certainty).

• Short‐term treatment with proton pump inhibitors, H2‐receptor antagonists and prokinetics for gastro‐oesophageal… 2013 · Cochrane Headline outcomes only
  RR 0.66 [0.6, 0.73]
  7 studies · 3147 participants
  Moderate

Intervention not reported

The intervention may leads to lower PPI versus prokinetic (low certainty).

• Short‐term treatment with proton pump inhibitors, H2‐receptor antagonists and prokinetics for gastro‐oesophageal… 2013 · Cochrane Headline outcomes only
  RR 0.53 [0.32, 0.87]
  2 studies · 747 participants
  Low

Intervention not reported

The intervention probably leads to lower PPI versus placebo (moderate certainty).

• Short‐term treatment with proton pump inhibitors, H2‐receptor antagonists and prokinetics for gastro‐oesophageal… 2013 · Cochrane Headline outcomes only
  RR 0.71 [0.65, 0.78]
  10 studies · 3710 participants
  Moderate

Intervention not reported

The intervention probably leads to lower H2RA versus placebo (moderate certainty).

• Short‐term treatment with proton pump inhibitors, H2‐receptor antagonists and prokinetics for gastro‐oesophageal… 2013 · Cochrane Headline outcomes only
  RR 0.84 [0.74, 0.95]
  2 studies · 514 participants
  Moderate

Intervention not reported

The intervention may leads to lower PPI versus H2RA (low certainty).

• Short‐term treatment with proton pump inhibitors, H2‐receptor antagonists and prokinetics for gastro‐oesophageal… 2013 · Cochrane Headline outcomes only
  RR 0.78 [0.62, 0.97]
  4 studies · 960 participants
  Low

Intervention not reported

The intervention may leads to lower PPI versus prokinetic (low certainty).

• Short‐term treatment with proton pump inhibitors, H2‐receptor antagonists and prokinetics for gastro‐oesophageal… 2013 · Cochrane Headline outcomes only
  RR 0.72 [0.56, 0.92]
  1 study · 302 participants
  Low