Findings

What do systematic reviews say?

33 questions · 33 findings · 3 reviews · Common Mental Disorders

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 18 · 54.5%Low 14 · 42.4%Moderate 1 · 3%High 0 · 0%

Comparison 12: SNRIs vs placebo

Reduction of of anxiety symptoms ‐ Clinician‐rated: LSAS avoidance subscale · adults with SAnD

1 finding from 1 review

Pharmacotherapy for social anxiety disorder (SAnD) 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 261 participants
Low

Comparison 12: SNRIs vs placebo

Reduction of of anxiety symptoms ‐ Clinician‐rated: LSAS fear subscale · adults with SAnD

1 finding from 1 review

Pharmacotherapy for social anxiety disorder (SAnD) 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 261 participants
Low

Comparison 13: SSRIs vs placebo

Reduction of of anxiety symptoms ‐ Clinician‐rated: LSAS total score · adults with SAnD

1 finding from 1 review

Pharmacotherapy for social anxiety disorder (SAnD) 2017 · Cochrane Headline outcomes only
no estimate extracted
14 studies · 1990 participants
Low

Comparison 13: SSRIs vs placebo

Reduction of of anxiety symptoms ‐ Clinician‐rated: LSAS avoidance subscale · adults with SAnD

1 finding from 1 review

Pharmacotherapy for social anxiety disorder (SAnD) 2017 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 1173 participants
Low

Comparison 13: SSRIs vs placebo

Reduction of of anxiety symptoms ‐ Clinician‐rated: LSAS fear subscale · adults with SAnD

1 finding from 1 review

Pharmacotherapy for social anxiety disorder (SAnD) 2017 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 1173 participants
Low

Comparison 2: anticonvulsants/GABAs vs placebo

Reduction of of anxiety symptoms ‐ Clinician‐rated: LSAS total score · adults with SAnD

1 finding from 1 review

Pharmacotherapy for social anxiety disorder (SAnD) 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 69 participants
Low

Comparison 15: NK1 receptor antagonist GR205171 vs placebo

Reduction of of anxiety symptoms ‐ Clinician‐rated: LSAS total score · adults with SAnD

1 finding from 1 review

Pharmacotherapy for social anxiety disorder (SAnD) 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 24 participants
Very low

Comparison 16: LY686017 vs placebo

Reduction of of anxiety symptoms ‐ Clinician‐rated: LSAS total score · adults with SAnD

1 finding from 1 review

Pharmacotherapy for social anxiety disorder (SAnD) 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 99 participants
Very low

Comparison 2: anticonvulsants/GABAs vs placebo

Reduction of of anxiety symptoms ‐ Clinician‐rated: LSAS avoidance subscale · adults with SAnD

1 finding from 1 review

Pharmacotherapy for social anxiety disorder (SAnD) 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 69 participants
Low

Comparison 2: anticonvulsants/GABAs vs placebo

Reduction of of anxiety symptoms ‐ Clinician‐rated: LSAS fear subscale · adults with SAnD

1 finding from 1 review

Pharmacotherapy for social anxiety disorder (SAnD) 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 69 participants
Low

Paroxetine vs placebo

Symptom severity reductionLSAS · people with anxiety and comorbid alcohol use disorders

1 finding from 1 review

Pharmacotherapy for anxiety and comorbid alcohol use disorders 2015 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 44 participants
Very low

Paroxetine vs placebo

Depression symptom reduction · people with anxiety and comorbid alcohol use disorders

1 finding from 1 review

Pharmacotherapy for anxiety and comorbid alcohol use disorders 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 15 participants
Very low

Glutamate modulators vs placebo

Reduction of TTM symptom severityMassachusetts General Hospital Hair‐Pulling Scale (MGH‐HPS) · children and adolescents with trichotillomania

1 finding from 1 review

Pharmacotherapy for trichotillomania 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 39 participants
Low