Probiotics vs placebo
It is very uncertain whether probiotics changes induction of remission compared with placebo (very low certainty).
- RR 1.06 [0.65, 1.71]2 studies · 46 participantsVery low
It is very uncertain whether probiotics changes induction of remission compared with placebo (very low certainty).
It is very uncertain whether probiotics changes adverse events leading to withdrawal compared with placebo (very low certainty).
It is very uncertain whether probiotics changes clinical relapse (12 to 52 weeks) compared with placebo (very low certainty).
It is very uncertain whether probiotics changes withdrawal due to adverse events (52 weeks) compared with 5‐aminosalicylic acid (5‐ASA) (mesalazine) (very low certainty).
The review found no eligible studies for this question.
It is very uncertain whether probiotics changes maintenance of clinical remission (52 weeks) compared with placebo (very low certainty).
The review found no eligible studies for this question.
Probiotics showed no clear difference in clinical relapse (52 weeks) compared with 5‐aminosalicylic acid (5‐ASA) (mesalazine) (low certainty).
Probiotics showed no clear difference in maintenance of clinical remission (52 weeks) compared with 5‐aminosalicylic acid (5‐ASA) (mesalazine) (low certainty).
It is very uncertain whether probiotics changes serious adverse events (52 weeks) compared with 5‐aminosalicylic acid (5‐ASA) (mesalazine) (very low certainty).
Probiotics probably leads to lower incidence CDAD: complete case compared with control (moderate certainty).
Probiotics showed no clear difference in CDAD (baseline risk 0‐2%) compared with control (moderate certainty).
Probiotics showed no clear difference in CDAD (baseline risk 3‐5%) compared with control (low certainty).
Probiotics probably leads to lower CDAD (baseline risk >5%) compared with control (moderate certainty).
Probiotics showed no clear difference in incidence of C. difficile infection: complete case compared with control (moderate certainty).