Cochrane · systematic review · CD006634

Probiotics for induction of remission in Crohn's disease

Limketkai, BN, Akobeng, AK, Gordon, M, et al. · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library

GutAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
2
current version
GRADE rated
2
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 2 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Probiotics compared to placebo for induction of remission in Crohn's disease

Population: induction of remission in Crohn's disease
2 questions
OutcomeEffectEvidenceStatus / GRADE
Induction of remission
Probiotics vs placebo
RR 1.06 [0.65, 1.71]2 studies · 46 participantsVery low
Downgraded: risk of bias
Adverse events leading to withdrawal
Probiotics vs placebo
RR 2.55 [0.11, 58.6]2 studies · 35 participantsVery low
Downgraded: risk of bias