Findings

What do systematic reviews say?

40 questions · 41 findings · 2 reviews · Airways

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No studies found 7 · 17.1%GRADE not reported 3 · 7.3%Very low 11 · 26.8%Low 12 · 29.3%Moderate 4 · 9.8%High 4 · 9.8%

Adaptive servo ventilation (ASV) plus best supportive care vs best supportive care alone or inactive control

All‐cause mortality ‐ up to 80 months Number of participants: 1355(2 RCTs)

Adaptive servo ventilation (ASV) plus best supportive care showed no clear difference in all‐cause mortality ‐ up to 80 months Number of participants: 1355(2… compared with best supportive care alone or inactive control (low certainty).

1 finding from 1 review

Non‐invasive positive pressure ventilation for central sleep apnoea in adults 2022 · Cochrane Headline outcomes only
RR 0.56 [0.06, 4.93]
Studies not reported
Low

Adaptive servo ventilation (ASV) plus best supportive care vs best supportive care alone or inactive control

Time to life‐saving cardiovascular intervention

The review found no eligible studies for this question.

1 finding from 1 review

Non‐invasive positive pressure ventilation for central sleep apnoea in adults 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Educational intervention vs control

Machine usage Hours per night · adults with obstructive sleep apnoea

1 finding from 1 review

Educational, supportive and behavioural interventions to improve usage of continuous positive airway pressure machines… 2020 · Cochrane Headline outcomes only
no estimate extracted
10 studies · 1128 participants
Very low

Behavioural intervention vs control

Machine usage Hours per night · adults with obstructive sleep apnoea

1 finding from 1 review

Educational, supportive and behavioural interventions to improve usage of continuous positive airway pressure machines… 2020 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 578 participants
High

Behavioural intervention vs control

1.2 CPAP device usage (hours/night), sensitivity analysis: adherence in control group < four hours/night · adults with obstructive sleep apnoea

1 finding from 1 review

Educational, supportive and behavioural interventions to improve usage of continuous positive airway pressure machines… 2020 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 525 participants
Moderate

Behavioural intervention vs control

N deemed adherent (≥4 hours/night) · adults with obstructive sleep apnoea

Behavioural intervention leads to higher 3.3 N deemed adherent (≥ four hours/night) compared with control (high certainty).

1 finding from 1 review

Educational, supportive and behavioural interventions to improve usage of continuous positive airway pressure machines… 2020 · Cochrane Headline outcomes only
OR 1.7 [1.2, 2.41]
6 studies · 549 participants
High

Behavioural intervention vs control

1.4 Withdrawal ‐ NO META‐ANALYSIS PERFORMED · adults with obstructive sleep apnoea

Behavioural intervention leads to lower 3.4 Withdrawal compared with control (high certainty).

1 finding from 1 review

Educational, supportive and behavioural interventions to improve usage of continuous positive airway pressure machines… 2020 · Cochrane Headline outcomes only
OR 0.66 [0.44, 0.98]
10 studies · 939 participants
High

Behavioural intervention vs control

Daytime sleepiness (ESS): endpoint score. · adults with obstructive sleep apnoea

1 finding from 1 review

Educational, supportive and behavioural interventions to improve usage of continuous positive airway pressure machines… 2020 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 271 participants
Low

Behavioural intervention vs control

AHI · adults with obstructive sleep apnoea

1 finding from 1 review

Educational, supportive and behavioural interventions to improve usage of continuous positive airway pressure machines… 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 89 participants
Very low

Behavioural intervention vs control

QoL · adults with obstructive sleep apnoea

2 findings from 1 review

Educational, supportive and behavioural interventions to improve usage of continuous positive airway pressure machines… 2020 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 228 participants
Moderate
Educational, supportive and behavioural interventions to improve usage of continuous positive airway pressure machines… 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 200 participants
GRADE not reported

Educational intervention vs control

1.2 CPAP device usage (hours/night), sensitivity analysis: adherence in control group < four hours/night · adults with obstructive sleep apnoea

1 finding from 1 review

Educational, supportive and behavioural interventions to improve usage of continuous positive airway pressure machines… 2020 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 698 participants
Very low

Mixed (BEH/EDU/SUP) intervention vs control

Machine usage Hours per night · adults with obstructive sleep apnoea

1 finding from 1 review

Educational, supportive and behavioural interventions to improve usage of continuous positive airway pressure machines… 2020 · Cochrane Headline outcomes only
no estimate extracted
11 studies · 4509 participants
Very low

Mixed (BEH/EDU/SUP) intervention vs control

1.2 CPAP device usage (hours/night), sensitivity analysis: adherence in control group < four hours/night · adults with obstructive sleep apnoea

1 finding from 1 review

Educational, supportive and behavioural interventions to improve usage of continuous positive airway pressure machines… 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 343 participants
Very low

Mixed (BEH/EDU/SUP) intervention vs control

N deemed adherent (≥4 hours/night) · adults with obstructive sleep apnoea

It is very uncertain whether mixed (BEH/EDU/SUP) intervention changes 4.3 N deemed adherent (≥ four hours/night) compared with control (very low certainty).

1 finding from 1 review

Educational, supportive and behavioural interventions to improve usage of continuous positive airway pressure machines… 2020 · Cochrane Headline outcomes only
OR 1.71 [1.08, 2.72]
9 studies · 4015 participants
Very low

Mixed (BEH/EDU/SUP) intervention vs control

1.4 Withdrawal ‐ NO META‐ANALYSIS PERFORMED · adults with obstructive sleep apnoea

It is very uncertain whether mixed (BEH/EDU/SUP) intervention changes 4.4 Withdrawal compared with control (very low certainty).

1 finding from 1 review

Educational, supportive and behavioural interventions to improve usage of continuous positive airway pressure machines… 2020 · Cochrane Headline outcomes only
OR 0.61 [0.28, 1.3]
11 studies · 4956 participants
Very low

Mixed (BEH/EDU/SUP) intervention vs control

QoL · adults with obstructive sleep apnoea

1 finding from 1 review

Educational, supportive and behavioural interventions to improve usage of continuous positive airway pressure machines… 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 3012 participants
Low

Mixed (BEH/EDU/SUP) intervention vs control

Anxiety · adults with obstructive sleep apnoea

1 finding from 1 review

Educational, supportive and behavioural interventions to improve usage of continuous positive airway pressure machines… 2020 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 333 participants
Very low

Educational intervention vs control

N deemed adherent (≥4 hours/night) · adults with obstructive sleep apnoea

It is very uncertain whether educational intervention changes 1.3 N deemed adherent (≥ four hours/night) compared with control (very low certainty).

1 finding from 1 review

Educational, supportive and behavioural interventions to improve usage of continuous positive airway pressure machines… 2020 · Cochrane Headline outcomes only
OR 2.58 [1.5, 4.44]
7 studies · 1019 participants
Very low

Educational intervention vs control

1.4 Withdrawal ‐ NO META‐ANALYSIS PERFORMED · adults with obstructive sleep apnoea

1 finding from 1 review

Educational, supportive and behavioural interventions to improve usage of continuous positive airway pressure machines… 2020 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 1745 participants
GRADE not reported

Educational intervention vs control

1.5 ESS ‐ Comparison of values at endpoint‐ NO META‐ANALYSIS PERFORMED · adults with obstructive sleep apnoea

1 finding from 1 review

Educational, supportive and behavioural interventions to improve usage of continuous positive airway pressure machines… 2020 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 355 participants
GRADE not reported