Adverse effects (side effects; treatment withdrawals) · Patients with radiation-induced salivary gland dysfunction
1 finding from 1 review
Johnson 1993 (5 mg tds): sweating 37%, headache 15%, urinary frequency 14%, vasodilatation 12%, dizziness 10%, dyspepsia 10%, nausea 8%, asthenia 8%, diarrhoea 5%; 6% withdrew at 5 mg tds and 29% at 10 mg tds. LeVeque…
2 studies · 278 participants
GRADE not reported
Other oral symptoms (dysgeusia, dysphagia) · Patients with radiation-induced salivary gland dysfunction
1 finding from 1 review
Dry mouth (xerostomia) · Patients with radiation-induced salivary gland dysfunction
1 finding from 1 review
Davies 1994 (cross-over, 20 participants): mean improvement in VAS score 22.5 mm with pilocarpine vs 15.2 mm with artificial saliva (100 mm scale). The improvement was greater with pilocarpine but was not statistically…
1 study · 20 participants
GRADE not reported
Adverse effects (side effects; treatment withdrawals) · Patients with radiation-induced salivary gland dysfunction
1 finding from 1 review
Davies 1994: main side effects with pilocarpine were nausea 20%, sweating 15%, lacrimation 10%. One participant definitely withdrew because of side effects; another may have.
1 study · 20 participants
GRADE not reported
Symptomatic improvement · adults with dry eye syndrome
It is very uncertain whether summary of findings: punctal plugs changes symptomatic improvement compared with oral pilocarpine (very low certainty).
1 finding from 1 review
Ocular surface staining · adults with dry eye syndrome
1 finding from 1 review
Aqueous tear production · adults with dry eye syndrome
1 finding from 1 review
Tear film stability · adults with dry eye syndrome
The review found no eligible studies for this question.
1 finding from 1 review
Artificial tear use · adults with dry eye syndrome
The review found no eligible studies for this question.
1 finding from 1 review
Adverse events · adults with dry eye syndrome
1 finding from 1 review
IOP increase of ≥ 5 mmHg within 2 hours · people with glaucoma receiving LTP
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
IOP increase of ≥ 10 mmHg within 2 hours · people with glaucoma receiving LTP
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Mean change in IOP from pre‐LTP within 2 hours · people with glaucoma receiving LTP
1 finding from 1 review
IOP increase of ≥ 5 mmHg between 2 and 24 hours · people with glaucoma receiving LTP
1 finding from 1 review
no estimate extracted
Studies not reported
Low
IOP increase of ≥ 10 mmHg between 2 and 24 hours · people with glaucoma receiving LTP
Apraclonidine showed no clear difference in IOP increase of ≥ 10 mmHg between 2 and 24 hours compared with pilocarpine (low certainty).
1 finding from 1 review
Mean change in IOP from pre‐LTP between 2 and 24 hours · people with glaucoma receiving LTP
1 finding from 1 review
Adverse events during treatment period · people with glaucoma receiving LTP
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found