Findings

What do systematic reviews say?

30 questions · 30 findings · 1 reviews · Emergency and Critical Care

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No studies found 14 · 46.7%GRADE not reported 0 · 0%Very low 10 · 33.3%Low 3 · 10%Moderate 3 · 10%High 0 · 0%

Beta‐agonist vs control

Ventilator‐free days up to day 28 · adults with acute respiratory distress syndrome

1 finding from 1 review

Pharmacological agents for adults with acute respiratory distress syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 646 participants
Very low

Beta‐agonist vs control

Discontinuation of medication due to adverse events · adults with acute respiratory distress syndrome

1 finding from 1 review

Pharmacological agents for adults with acute respiratory distress syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 606 participants
Very low

Corticosteroids vs control

Duration of mechanical ventilation · adults with acute respiratory distress syndrome

1 finding from 1 review

Pharmacological agents for adults with acute respiratory distress syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 277 participants
Very low

Beta‐agonist vs control

Fitness to return to work at 12 months · adults with acute respiratory distress syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological agents for adults with acute respiratory distress syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Corticosteroids vs control

Ventilator‐free days up to day 28 · adults with acute respiratory distress syndrome

1 finding from 1 review

Pharmacological agents for adults with acute respiratory distress syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 494 participants
Low

Adverse events Defined as leading to discontinuation of study medication; or for studies with standard care control, defined by study authors as "serious adverse events" · adults with acute respiratory distress syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological agents for adults with acute respiratory distress syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Corticosteroids vs control

Fitness to return to work at 12 months · adults with acute respiratory distress syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological agents for adults with acute respiratory distress syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Surfactants vs control

Early all‐cause mortality (≤ 3 months) Reported at: 28 days; and 90 days. Time point not reported in 4 studies · adults with acute respiratory distress syndrome

It is very uncertain whether surfactants changes early all‐cause mortality (≤ 3 months) Reported at: 28 days; and 90… compared with control (very low certainty).

1 finding from 1 review

Pharmacological agents for adults with acute respiratory distress syndrome 2019 · Cochrane Headline outcomes only
RR 1.08 [0.91, 1.29]
9 studies · 1338 participants
Very low

Surfactants vs control

Late all‐cause mortality ( > 3 months · adults with acute respiratory distress syndrome

It is very uncertain whether surfactants changes late all‐cause mortality ( > 3 months) Reported at: 180 days compared with control (very low certainty).

1 finding from 1 review

Pharmacological agents for adults with acute respiratory distress syndrome 2019 · Cochrane Headline outcomes only
RR 1.28 [1.01, 1.61]
1 study · 418 participants
Very low

Surfactants vs control

Duration of mechanical ventilation · adults with acute respiratory distress syndrome

1 finding from 1 review

Pharmacological agents for adults with acute respiratory distress syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 16 participants
Very low