Findings

What do systematic reviews say?

32 questions · 32 findings · 3 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 12 · 37.5%Low 13 · 40.6%Moderate 7 · 21.9%High 0 · 0%

Intervention not reported

Hb (g/L) ‐ before further donation Scale from: 123 to 152 · patients with iron deficiency and/or anaemia in blood donors

1 finding from 1 review

Oral or parenteral iron supplementation to reduce deferral, iron deficiency and/or anaemia in blood donors 2014 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 847 participants
Moderate

Intervention not reported

Hb (g/L) ‐ after subsequent donation(s) Scale from: 127.3 to 129 · patients with iron deficiency and/or anaemia in blood donors

1 finding from 1 review

Oral or parenteral iron supplementation to reduce deferral, iron deficiency and/or anaemia in blood donors 2014 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 406 participants
Moderate

Intervention not reported

Serum ferritin (ng/mL) ‐ before further donation Scale from: 12.9 to 57.8 · patients with iron deficiency and/or anaemia in blood donors

1 finding from 1 review

Oral or parenteral iron supplementation to reduce deferral, iron deficiency and/or anaemia in blood donors 2014 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 640 participants
Moderate

Intervention not reported

Serum ferritin (ng/mL) ‐ after subsequent donation(s) Scale from: 18 to 19 · patients with iron deficiency and/or anaemia in blood donors

1 finding from 1 review

Oral or parenteral iron supplementation to reduce deferral, iron deficiency and/or anaemia in blood donors 2014 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 619 participants
Moderate

Intervention not reported

Adverse effects (any) · patients with iron deficiency and/or anaemia in blood donors

The intervention probably leads to higher adverse effects (any) (moderate certainty).

1 finding from 1 review

Oral or parenteral iron supplementation to reduce deferral, iron deficiency and/or anaemia in blood donors 2014 · Cochrane Headline outcomes only
RR 1.6 [1.23, 2.07]
4 studies · 1748 participants
Moderate

Intervention not reported

Ferritin: final or change (µg/L) · adults and children with CKD

1 finding from 1 review

Parenteral versus oral iron therapy for adults and children with chronic kidney disease 2019 · Cochrane Headline outcomes only
no estimate extracted
33 studies · 3389 participants
Low

Intervention not reported

TSAT: final or change (%) · adults and children with CKD

1 finding from 1 review

Parenteral versus oral iron therapy for adults and children with chronic kidney disease 2019 · Cochrane Headline outcomes only
no estimate extracted
27 studies · 3089 participants
Low

Intervention not reported

HCT (%) · adults and children with CKD

1 finding from 1 review

Parenteral versus oral iron therapy for adults and children with chronic kidney disease 2019 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 152 participants
Very low

Intervention not reported

ESA dose: final or change · adults and children with CKD

1 finding from 1 review

Parenteral versus oral iron therapy for adults and children with chronic kidney disease 2019 · Cochrane Headline outcomes only
no estimate extracted
11 studies · 522 participants
Low

Intervention not reported

eGFR: final or change (mL/min) · adults and children with CKD

1 finding from 1 review

Parenteral versus oral iron therapy for adults and children with chronic kidney disease 2019 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 1052 participants
Low

Intervention not reported

Number achieving target Hb or increase ≥1 g/dL · adults and children with CKD

The intervention may leads to higher number achieving target Hb or increase ≥1 g/dL (low certainty).

1 finding from 1 review

Parenteral versus oral iron therapy for adults and children with chronic kidney disease 2019 · Cochrane Headline outcomes only
RR 1.71 [1.43, 2.04]
13 studies · 2206 participants
Low

Intervention not reported

Hb: final or change (g/dL) · adults and children with CKD

1 finding from 1 review

Parenteral versus oral iron therapy for adults and children with chronic kidney disease 2019 · Cochrane Headline outcomes only
no estimate extracted
31 studies · 3373 participants
Low