Findings

What do systematic reviews say?

30 questions · 30 findings · 3 reviews · Neonatal

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No studies found 11 · 36.7%GRADE not reported 0 · 0%Very low 2 · 6.7%Low 14 · 46.7%Moderate 3 · 10%High 0 · 0%

Morphine vs paracetamol

Major neurodevelopmental disability in children aged 3 to 5 years CA · postoperative pain in preterm and term infants

The review found no eligible studies for this question.

1 finding from 1 review

Systemic opioids versus other analgesics and sedatives for postoperative pain in neonates 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Morphine vs paracetamol

Cognitive and educational outcomes in children more than five years old · postoperative pain in preterm and term infants

The review found no eligible studies for this question.

1 finding from 1 review

Systemic opioids versus other analgesics and sedatives for postoperative pain in neonates 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Morphine vs paracetamol

All‐cause mortality during hospital stay · postoperative pain in preterm and term infants

The review found no eligible studies for this question.

1 finding from 1 review

Systemic opioids versus other analgesics and sedatives for postoperative pain in neonates 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Morphine vs paracetamol

Severe (defined as stage 3 or greater) retinopathy of prematurity ‐ not reported · postoperative pain in preterm and term infants

The review found no eligible studies for this question.

1 finding from 1 review

Systemic opioids versus other analgesics and sedatives for postoperative pain in neonates 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Morphine vs paracetamol

Severe (grade 3 or greater) intraventricular hemorrhage (IVH) on cranial ultrasound ‐ not reported · postoperative pain in preterm and term infants

The review found no eligible studies for this question.

1 finding from 1 review

Systemic opioids versus other analgesics and sedatives for postoperative pain in neonates 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

PIPP score (difference between baseline and heel lance period) · Neonates

1 finding from 1 review

Paracetamol (acetaminophen) for prevention or treatment of pain in newborns 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 72 participants
Low

Intervention not reported

Duration of crying (seconds) during the first 3 minutes · Neonates

1 finding from 1 review

Paracetamol (acetaminophen) for prevention or treatment of pain in newborns 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 72 participants
Low

Intervention not reported

PIPP (maximum score within 3 minutes following lancing) · Neonates

1 finding from 1 review

Paracetamol (acetaminophen) for prevention or treatment of pain in newborns 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 38 participants
Low

Intervention not reported

PIPP score in first 45 seconds of eye examination · Neonates

1 finding from 1 review

Paracetamol (acetaminophen) for prevention or treatment of pain in newborns 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 80 participants
Low

Intervention not reported

PIPP score 5 minutes after eye examination · Neonates

1 finding from 1 review

Paracetamol (acetaminophen) for prevention or treatment of pain in newborns 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 11 participants
Very low