Overall success (composite of clinical and radiographic success) · Human permanent teeth with irreversible pulpitis due to carious pulp exposure
Biodentine had a significantly higher pulpotomy success rate than MTA (indirect comparison; numeric estimate not available); ungraded.
1 finding from 1 review
Pulp necrosis · Vital teeth
The pooled incidence with radiographic assessment was 4.95%.
2 findings from 1 review
Proportion 4.95 [2.43, 8.29]
5 studies · 1853 participants
GRADE not reported
Proportion 5.66 [3.71, 7.99]
24 studies · 6581 participants
GRADE not reported
Overall success (composite of clinical and radiographic success) · Adults (>=18 y) with mature permanent teeth, carious exposure and normal/reversibly inflamed pulp
At 1 year, partial pulpotomy and direct pulp capping (both calcium hydroxide) gave similarly low success in reversibly inflamed pulps (34.5% vs 31.8%; ungraded, single trial).
2 findings from 1 review
Success rate (%) 34.5 vs 31.8
1 study · 51 participants
GRADE not reported
Success rate (%) 11.1 vs 5.9
1 study · 44 participants
GRADE not reported
Overall success (composite of clinical and radiographic success) · Human permanent teeth with irreversible pulpitis due to carious pulp exposure
CEM and calcium hydroxide did not differ significantly in pulpotomy success (indirect comparison); ungraded.
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Human permanent teeth with irreversible pulpitis due to carious pulp exposure
MTA and CEM did not differ significantly in pulpotomy success (indirect comparison); ungraded.
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Human permanent teeth with irreversible pulpitis due to carious pulp exposure
MTA had a significantly higher pulpotomy success rate than calcium hydroxide (indirect comparison; numeric estimate not available); ungraded.
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Adults aged 18 years or older with mature permanent teeth and carious pulp exposure
In the high-risk-study-excluded sensitivity meta-regression, longer follow-up was associated with lower success.
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Adults aged 18 years or older with mature permanent teeth and carious pulp exposure
Partial pulpotomy with tri-calcium silicate cements (MTA/Biodentine) has a much higher success rate than with calcium hydroxide in adults (86.8% vs 34.3%; ungraded).
2 findings from 1 review
Overall success (composite of clinical and radiographic success) · Adults (>=18 y) with mature permanent teeth and deep carious pulp exposure
Using NaOCl during partial pulpotomy is associated with borderline-higher success, independent of concentration (ungraded, exploratory).
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Adults (>=18 y) with mature permanent teeth and deep carious pulp exposure
Immediate permanent restoration after partial pulpotomy is associated with much higher success than delayed restoration (89.9% immediate vs 23.2% beyond 14 days; ungraded).
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Adults aged 18 years or older with mature permanent teeth and carious pulp exposure
Each additional day before permanent restoration was associated with a 0.088% decrease in success in meta-regression.
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Adults (18-45 y) with mature permanent molars, carious exposure and symptomatic irreversible pulpitis
Restricting the lateral extent of partial pulpotomy gives success equivalent to more extensive amputation (97.6% vs 97.5%, p>0.05; ungraded, single trial).
1 finding from 1 review
Postoperative pain and analgesic intake · Adults (18-45 y) with mature permanent molars, carious exposure and symptomatic irreversible pulpitis
Restricted partial pulpotomy causes less early postoperative pain and analgesic use than extended amputation (p<0.05; ungraded, single trial).
1 finding from 1 review
Same RCT (Ramani 2024): restricted PP had significantly lower postoperative pain scores on days 1 and 2 (p<0.05) and required significantly less analgesic intake (p<0.05) than extended PP.
1 study · 96 participants
GRADE not reported
Patient- and clinical-reported outcomes (tooth survival, clinical/radiographic success, pain) · Asymptomatic permanent teeth with deep caries (no symptoms)
No studies compared partial versus full pulpotomy in asymptomatic permanent teeth with deep caries, so no evidence is available.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Overall success (composite of clinical and radiographic success) · Permanent teeth with carious pulp exposure
Hemostasis within 6 min gave the highest success (90.4%), but the difference across hemostasis-time groups was not significant (ungraded).
13 findings from 1 review
Show 10 more findings
Proportion 0.856
Studies not reported
GRADE not reported
Proportion 0.862
Studies not reported
GRADE not reported
Proportion 0.824 [0.746, 0.890]
Studies not reported
GRADE not reported
Proportion 0.909 [0.833, 0.965]
Studies not reported
GRADE not reported
Proportion 0.882
Studies not reported
GRADE not reported
Proportion 0.867 [0.820, 0.907]
25 studies · 2012 participants
Very low
Proportion 0.902
Studies not reported
GRADE not reported
Proportion 0.838 [0.759, 0.904]
Studies not reported
GRADE not reported
Proportion 0.872 [0.803, 0.929]
Studies not reported
GRADE not reported
Proportion 0.859
Studies not reported
GRADE not reported
Overall success (composite of clinical and radiographic success) · Human permanent teeth with irreversible pulpitis due to carious pulp exposure
Among 6 observational studies, pooled pulpotomy success was 92.6 per 100 (95% CI 0.86-0.96), very low certainty.
4 findings from 1 review
Show 1 more finding
Overall success (composite of clinical and radiographic success) · Human permanent teeth with asymptomatic irreversible pulpitis due to carious pulp exposure
In asymptomatic irreversible pulpitis, pooled pulpotomy success was 91.3% (95% CI 80-96.5%); ungraded.
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Human permanent teeth with irreversible pulpitis and open (immature) root apex due to carious pulp exposure
In open-apex teeth, pooled pulpotomy success was 95.8% (95% CI 81-99%); significantly higher than closed apex (z=2.33, p=0.02); ungraded.
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Human permanent teeth with irreversible pulpitis and closed (mature) root apex due to carious pulp exposure
In closed-apex teeth, pooled pulpotomy success was 83% (95% CI 69-91%); significantly lower than open apex (z=2.33, p=0.02); ungraded.
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Human permanent teeth with symptomatic irreversible pulpitis due to carious pulp exposure
In symptomatic irreversible pulpitis, pooled pulpotomy success was 84% (95% CI 72-92%); not significantly different from asymptomatic (z=-1.34, p=0.18); ungraded.
1 finding from 1 review