Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

135 questions · 156 findings · 30 reviews · All outcomes

No studies found 66 · 42.3%GRADE not reported 61 · 39.1%Very low 15 · 9.6%Low 13 · 8.3%Moderate 0 · 0%High 1 · 0.6%

Pre-cooling of the injection site vs Conventional treatment

Intraoperative pain · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia
1 finding from 1 review

Video modelling acclimatisation vs Acclimatisation in clinic (tell-show-do)

Self- or observational assessment of intraoperative distress/pain/acceptance of treatment during provision of LA: pain-related behaviour during LA (negative vs positive behaviour; Frankl Behaviour Rating Scale) · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

It is very uncertain whether video modelling acclimatisation changes self- or observational assessment of intraoperative… compared with acclimatisation in clinic (tell-show-do) (very low certainty).

1 finding from 1 review

Camouflage syringe vs Conventional syringe

Acceptance of LA · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

The review found no eligible studies for this question.

1 finding from 1 review

Pre-cooling of the injection site vs Conventional treatment

Acceptance of LA · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

The review found no eligible studies for this question.

1 finding from 1 review

Counter-stimulation or distraction vs Conventional treatment

Intraoperative pain · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

It is very uncertain whether counter-stimulation or distraction changes self- or observational assessment of intraoperative… compared with conventional treatment (very low certainty).

1 finding from 1 review

The wand (computer-controlled LA delivery system) vs Sleeper One (electronic LA delivery system)

Self- or observational assessment of intraoperative distress/pain/acceptance of treatment during provision of LA: pain-related behaviour (any disruptive behaviour/sudden reaction/movement) · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

It is very uncertain whether the wand (computer-controlled LA delivery system) changes self- or observational assessment of intraoperative… compared with sleeper One (electronic LA delivery system) (very low certainty).

1 finding from 1 review

Fixed-appliance orthodontic treatment incorporating surgically assisted orthodontics (adjunctive surgical procedure: corticotomy, micro-osteoperforation or interseptal bone reduction) to increase the rate of tooth movement vs Conventional orthodontic appliance treatment

Duration of orthodontic treatment, number of visits during active treatment (scheduled and unscheduled) and duration of visits · Individuals of any age receiving orthodontic treatment with fixed appliances (braces) (people requiring orthodontic tooth movement);…

The review found no eligible studies for this question.

1 finding from 1 review

Fixed-appliance orthodontic treatment incorporating surgically assisted orthodontics (adjunctive surgical procedure: corticotomy, micro-osteoperforation or interseptal bone reduction) to increase the rate of tooth movement vs Conventional orthodontic appliance treatment

Patient satisfaction with treatment Measured by a validated scale · Individuals of any age receiving orthodontic treatment with fixed appliances (braces) (people requiring orthodontic tooth movement);…

The review found no eligible studies for this question.

1 finding from 1 review

Fixed-appliance orthodontic treatment incorporating surgically assisted orthodontics (adjunctive surgical procedure: corticotomy, micro-osteoperforation or interseptal bone reduction) to increase the rate of tooth movement vs Conventional orthodontic appliance treatment

Prolonged stability of treatment (adjudged using an accepted scale) · Individuals of any age receiving orthodontic treatment with fixed appliances (braces) (people requiring orthodontic tooth movement);…

The review found no eligible studies for this question.

1 finding from 1 review

Fixed-appliance orthodontic treatment incorporating surgically assisted orthodontics (adjunctive surgical procedure: corticotomy, micro-osteoperforation or interseptal bone reduction) to increase the rate of tooth movement vs Conventional orthodontic appliance treatment

Rate of orthodontic tooth movement with removable orthodontic aligners · Individuals of any age receiving orthodontic treatment with fixed appliances (braces) (people requiring orthodontic tooth movement);…

Fixed-appliance orthodontic treatment incorporating surgically… may leads to higher rate of tooth movement (orthodontic tooth movement in mm at 3 months) compared with conventional treatment: fixed-appliance orthodontic treatment… (low certainty).

2 findings from 1 review

Fixed-appliance orthodontic treatment incorporating surgically assisted orthodontics (adjunctive surgical procedure: corticotomy, micro-osteoperforation or interseptal bone reduction) to increase the rate of tooth movement vs Conventional orthodontic appliance treatment

Harms arising during orthodontic treatment (gingival and periodontal problems, anchorage loss and iatrogenic damage to teeth e.g. caries/decalcification, root resorption); only periodontal/gingival health assessed · Individuals of any age receiving orthodontic treatment with fixed appliances (braces) (people requiring orthodontic tooth movement);…
1 finding from 1 review
  • SoF: Assumed risk 'See comment'; Corresponding risk 'See comment'; 13 (1 study, split‐mouth); Quality ⊕⊖⊖⊖ very low. Comment: 'Gingival and periodonal problems only were assesed in 1 study (Aboul‐Ela 2011). No precise…
    1 study · 13 participants
    Very low

Fixed-appliance orthodontic treatment incorporating surgically assisted orthodontics (adjunctive surgical procedure: corticotomy, micro-osteoperforation or interseptal bone reduction) to increase the rate of tooth movement vs Conventional orthodontic appliance treatment

Discomfort/pain · Individuals of any age receiving orthodontic treatment with fixed appliances (braces) (people requiring orthodontic tooth movement);…
1 finding from 1 review
  • Surgical adjunctive procedures for accelerating orthodontic treatment 2015 · Cochrane All outcomes
    24 hours to 28 days
    Results: 'Pain experience was compared between surgical and non‐surgical cases in a single study (Alikhani 2013). Within 24 hours of appliance activation and canine retraction, both groups reported higher levels of…
    1 study
    GRADE not reported

Fixed-appliance orthodontic treatment incorporating surgically assisted orthodontics (adjunctive surgical procedure: corticotomy, micro-osteoperforation or interseptal bone reduction) to increase the rate of tooth movement vs Conventional orthodontic appliance treatment

Improvement in occlusion (Peer Assessment Rating (PAR) or other validated scale) · Individuals of any age receiving orthodontic treatment with fixed appliances (braces) (people requiring orthodontic tooth movement);…

The review found no eligible studies for this question.

1 finding from 1 review

Ion-releasing restorations (IRR): RMGIC, HVGIC, GIC, compomer/PMRC, giomer vs Composite resin (CR), including bulk-fill composite

Adequate marginal adaptation · Children receiving dental restorations (aged 4-11 years; primary teeth; Class I/II/V cavities)

No significant difference between IRR and CR in marginal adaptation (high certainty).

1 finding from 1 review

Strategies to integrate oral health into primary care (e.g., training/education of non-dental primary care professionals, policy/financing and health-insurance changes, colocation of dental and medical services, interprofessional and community-health-worker collaboration, teledentistry, integrated oral health assessment tools, school-based activities) vs No integration / usual care (or pre-integration baseline; many included studies uncontrolled)

Access to oral healthcare (referral pathways, documentation processes, operating efficiencies, staffing, visits for oral health issues, uptake of fluoride varnish/other preventive treatment, and visits to an oral health professional) · People of all ages and abilities served through primary care and related settings (children, pregnant women, older adults in…

Most strategies to integrate oral health into primary care were associated with improved access to oral healthcare (19 studies, narrative synthesis; ungraded).

1 finding from 1 review
  • Strategies to integrate oral health into primary care: a systematic review. 2023 All outcomes
    Primary care, community, school, and aged-care/residential/nursing-home settings
    Access to oral healthcare was the primary outcome most studied (n=19). Most studies reported results favouring the integration strategy, including improvements in referral pathways, documentation processes, operating…
    19 studies
    GRADE not reported

Any preprocedural mouth rinse vs Placebo, no rinsing or control

Acceptability and feasibility of the intervention to patients and dental healthcare providers · People undergoing aerosol-generating procedures (AGPs) in a dental setting

The review found no eligible studies for this question.

1 finding from 1 review

External control of fluoride concentration vs Not applicable

Water samples with fluoride concentration outside the acceptable range · Brazilian cities with artificially fluoridated public water supplies

After excluding Silva et al., the pooled prevalence outside the acceptable range was 47.1%.

1 finding from 1 review